Evidence map›Paper›PMID 38628190›Full record

ArticleFood science & nutrition2024

Probiotic yogurt regulates gut microbiota homeostasis and alleviates hepatic steatosis and liver injury induced by high-fat diet in golden hamsters.

Linwensi Zhu, Na Ying, Liuyi Hao, Ai Fu, Qinchao Ding, Feiwei Cao, Daxi Ren, Qiang Han, Songtao Li

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Linwensi ZhuThe First Affiliated Hospital of Zhejiang Chinese Medical University Zhejiang China.
Na YingSchool of Life Science Zhejiang Chinese Medical University Zhejiang China.
Liuyi HaoSchool of Public Health Zhejiang Chinese Medical University Hangzhou China.
Ai FuSchool of Life Science Zhejiang Chinese Medical University Zhejiang China.
Qinchao DingInstitute of Dairy Science, College of Animal Science Zhejiang University Zhejiang China.
Feiwei CaoSchool of Public Health Zhejiang Chinese Medical University Hangzhou China.
Daxi RenInstitute of Dairy Science, College of Animal Science Zhejiang University Zhejiang China.ORCID https://orcid.org/0000-0002-8016-0033
Qiang HanSchool of Public Health Zhejiang Chinese Medical University Hangzhou China.ORCID https://orcid.org/0000-0002-1445-4682
Songtao LiSchool of Public Health Zhejiang Chinese Medical University Hangzhou China.
Zhejiang Chinese Medical University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the beneficial effects of probiotic yogurt on lipid metabolism and gut microbiota in metabolic-related fatty liver disease (MAFLD) golden hamsters fed on a high-fat diet (HFD). The results demonstrated that probiotic yogurt significantly reversed the adverse effects caused by HFD, such as body and liver weight gain, liver steatosis and damage, sterol deposition, and oxidative stress after 8 weeks of intervention. qRT-PCR analysis showed that golden hamsters fed HFD had upregulated genes related to adipogenesis, increased free fatty acid infiltration, and downregulated genes related to lipolysis and very low-density lipoprotein secretion. Probiotic yogurt supplements significantly inhibited HFD-induced changes in the expression of lipid metabolism-related genes. Furthermore, 16S rRNA gene sequencing of the intestinal content microbiota suggested that probiotic yogurt changed the diversity and composition of the gut microbiota in HFD-fed hamsters. Probiotic yogurt decreased the ratio of the

Indexed as

gut microbiotalipid metabolism regulationmetabolism‐related fatty liver diseaseprobiotic yogurt

Identifiers

PMID38628190
PMCPMC11016441
OpenAlexW4390609315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.