Evidence map›Paper›PMID 38628024›Full record

ArticleESC heart failure2024

Left ventricular reverse remodelling as a promising strategy for resolving left ventricular thrombus.

Xuefu Chen, Xinxin Zhang, Yahui Yang, Yuxi Sun, Jinping Si, Shufen Jiang, Yuze Hu, Zijie Ding, Yunlong Xia, Yanwei Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in ESC heart failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Xuefu ChenDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Xinxin ZhangDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yahui YangCollege of Pharmacy, Dalian Medical University, Dalian, China.
Yuxi SunDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Jinping SiDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Shufen JiangDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yuze HuDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Zijie DingDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yunlong XiaDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Yanwei ChenDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Ying LiuDepartment of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Dalian Medical University · CNFirst Affiliated Hospital of Dalian Medical University · CNShandong Academy of Pharmaceutical Sciences · CNSichuan University · CN

Funding

National Natural Science Foundation of China 82170385National Natural Science Foundation of China U1908209
6 · The paper itself

Abstract

aimsRecent years, several studies have suggested that abnormal baseline left ventricular (LV) function and structure are associated with left ventricular thrombus (LVT) formation. Despite this, most studies have given less attention to the potential role of left ventricular reverse remodelling (LVRR), that is, the improvement of LV function and structure, in resolving LVT. In this study, we aim to investigate the clinical characteristics, prognosis, and LVT resolution in patients with LVRR. METHODS AND

resultsThis is a retrospective study conducted at The First Affiliated Hospital of Dalian Medical University. Our cohort consists of patients diagnosed with LVT between 1 November 2015 and 31 May 2020. Enrolled patients were categorized into two groups: LVRR and Failure of LVRR. The primary endpoints included LVT resolution and embolic events. A total of 84 patients were included in the study, with 59 patients in the LVRR group and 25 patients in the Failure of LVRR group. In our study, patients in the LVRR group experienced higher incidence of LVT resolution and a lower risk of embolic events. Multivariate logistic analysis revealed that Failure of LVRR was the only independent negative predictor for LVT resolution and positive predictor for embolic events.

conclusionsPatients with LVRR experience higher incidence of LVT resolution and have lower risk of embolic events, highlighting the significance of identifying and mitigating risk factors that contribute to abnormal LV function and structure in management of patients with LVT.

Indexed as

Heart VentriclesThrombosisVentricular Function, LeftVentricular RemodelingAgedEchocardiographyFemaleFollow-Up StudiesHeart DiseasesHumansMaleMiddle AgedPrognosisRetrospective StudiesVentricular Dysfunction, LeftEmbolic eventsLeft ventricular reverse remodellingLeft ventricular thrombusThrombus resolution

Identifiers

PMID38628024
PMCPMC11287347
OpenAlexW4394872834

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.