Evidence map›Paper›PMID 38627719›Full record

ArticleBMC oral health2024

Mean platelet volume is associated with periodontitis: a cross-sectional study.

Chenying Zhou, Ye Liu, Jingjing Bai, Yi Luo, Jukun Song, Ping Feng

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07069244 (Blood Markers in Periodontal Inflammation and Alzheimer's Disease), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07069244 completednot on this mapstarted 2025, after this paper: background citation

Blood Markers in Periodontal Inflammation and Alzheimer's Disease: A Retrospective Case-Control Study

TypeobservationalSponsorUskudar UniversityRan2025 to 2025Enrolled100ConditionsPeriodontal Disease, Periodontitis, Periodontal Inflammation, Biomarkers / BloodArmsComplete Blood Count Test, Periodontal examinations, Clinical Dementia Rating scale, Standardized Mini-Mental Test
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Chenying ZhouSchool of Stomatology, Zunyi Medical University, Zunyi, Guizhou, China.
Ye LiuSchool of Stomatology, Zunyi Medical University, Zunyi, Guizhou, China.
Jingjing BaiSchool of Stomatology, Zunyi Medical University, Zunyi, Guizhou, China.
Yi LuoGuiyang Hospital of Stomatology, Guiyang, Guizhou, China.
Jukun SongThe Affiliated Stomatological Hospital and Stomatology of Guizhou Medical University, Guizhou Medical University, Guiyang, China. songjukun@163.com.
Ping FengSchool of Stomatology, Zunyi Medical University, Zunyi, Guizhou, China. 398994584@qq.com.
Zunyi Medical University · CNGuiyang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is uncertain if mean platelet volume and periodontitis are related. The objective of this study was to examine the association between levels of mean platelet volume and moderate/severe periodontitis in adult persons who inhabit the U.S.

methodsWe screened 6,809 people from the National Health and Nutrition Examination Survey (NHANES 2009-2012). Mean platelet volume was measured in the Mobile Examination Centers (MECs) using the Beckman Coulter analyzer. The category of periodontitis was defined by the CDC/AAP using clinical periodontal parameters. Multiple logistic regression models were employed to examine the distribution for covariate differences across the various independent groups. Four models were employed to examine the relationship between mean platelet volume level and periodontitis. Smoothed curve fitting was utilized to confirm the linearity of the relationships. To determine the impact of factors on the connection between MPV and periodontitis, subgroup analysis and interaction testing were utilized.

resultsResults from the multiple logistic regression analysis indicate a significant association between moderate/severe periodontitis and the mean platelet level, even after considering any potential confounding variables (OR = 1.090, 95% CI: 1.019-1.166, P-value = 0.01211). Additionally, those in the upper tertile of mean platelet volume levels had a 21.6% higher probability of developing periodontitis when compared with those in the least tertile of mean platelet levels (OR = 1.216, 95% CI:1.052-1.406, P-value = 0.00816). Moreover, it showed a positive correlation between mean platelet volume (MPV) and moderate/severe periodontitis. Subgroup analyses indicated a positive association between the level of mean platelet volume and moderate/severe periodontitis among individuals who were under 60 years of age, had low income, were obese, never smoked, were heavy drinkers, had hypertension, and had no cardiovascular disease (p < 0.05). However, none of the subgroups exhibited significant interactions (p for interaction > 0.05).

conclusionA correlation has been found between mean platelet volume levels and periodontal disease in individuals residing in the United States.

Indexed as

Mean Platelet VolumePeriodontitisAdultBlood PlateletsCross-Sectional StudiesHumansNutrition SurveysUnited StatesCross-sectional studyMean platelet volumeNHANESPeriodontal health

Identifiers

PMID38627719
PMCPMC11020922
OpenAlexW4394849916

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.