Evidence map›Paper›PMID 38627619›Full record

ArticleBMC emergency medicine2024

A retrospective audit of adult and paediatric anaphylaxis management from two Australian metropolitan mixed emergency departments.

A Thomas, J Delic, P Hudson, M Batchelor, H Johannsen, L E Grzeskowiak

Open access · goldAbstract read
In one paragraph

Article in BMC emergency medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Triggers, clinical spectra and outcomes of pediatric anaphylaxis in a tertiary center: impact of comorbidities and cofactors on severity.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2026
    Article
  2. Article
  3. Mapping the Burden and Risk Factors of Allergic Diseases and Asthma Among Aboriginal and Torres Strait Islander People: A Scoping Review.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

A ThomasSA Pharmacy, Flinders Medical Centre, Southern Adelaide Local Health Network, Bedford Park, Australia, Flinders Drive, 5042. Alicia.Thomas@sa.gov.au.
J DelicEmergency Department, Flinders Medical Centre, Southern Adelaide Local Health Network, Bedford Park, Australia.
P HudsonAllergy/Clinical Immunology Department, Flinders Medical Centre, Southern Adelaide Local Health Network, Bedford Park, Australia.
M BatchelorAllergy/Clinical Immunology Department, Flinders Medical Centre, Southern Adelaide Local Health Network, Bedford Park, Australia.
H JohannsenCollege of Medicine and Public Health, Flinders University, Adelaide, Australia.
L E GrzeskowiakSA Pharmacy, Flinders Medical Centre, Southern Adelaide Local Health Network, Bedford Park, Australia, Flinders Drive, 5042.
Flinders Medical Centre · AUFlinders University · AU

Funding

Channel 7 Children's Research Foundation CRF-210323
6 · The paper itself

Abstract

backgroundAnaphylaxis is a potentially life-threatening allergic reaction, with presentations to emergency departments (EDs) increasing across Australia. Understanding the features of those presenting with anaphylaxis and aspects related to its optimal clinical management across the admission, treatment and discharge settings is needed to minimise its impact. We aimed to evaluate the nature and management of presentations related to anaphylaxis across two Australian EDs.

methodsRetrospective audit of paediatric and adult patients presenting to a community or tertiary level ED with anaphylaxis from 1 May 2018 to 30 April 2019. Data extracted from medical records included demographic characteristics, causative agents, clinical features, treatments administered across community, ambulance or ED settings, as well as post-discharge care arrangements including provision of Adrenaline Auto-Injector (AAI) and Allergy/Anaphylaxis Action Plan (AAP).

resultsA total of 369 (107 paediatric and 262 adult) ED presentations were identified. A total of 94 (36%) adult and 46 (43%) paediatric patients received pre-hospital adrenaline, with a further 91 (35%) adult and 29 (27%) paediatric patients receiving a dose of adrenaline in the ED. The most commonly administered treatment in ED were corticosteroids, given to 157 (60%) adult and 55 (51%) paediatric patients. Among those requiring an AAI for discharge, 123/210 (59%) adult and 57/91 (63%) of paediatric patients left hospital with an AAI. In contrast, among those requiring an allergy/anaphylaxis action plan (AAP) on discharge, 61/206 (30%) adult and 30/90 (33%) of paediatric patients left hospital with one. Factors associated with an increased likelihood of receiving AAI on discharge in paediatric and adult patients included receipt of any adrenaline, receipt of two or more doses of adrenaline, and longer duration of hospital stay. Adults presenting within business hours were more likely to be discharged with AAI, but no such difference was observed for paediatric patients. Similar findings were evident for provision of AAP on discharge.

conclusionThese findings demonstrate the need to improve assessment and treatment in the ED. In particular, the observed large variability in provision of AAI and AAP on discharge presents opportunities to explore strategies to improve awareness and provision of these critical components of post-discharge care.

Indexed as

AnaphylaxisAdultAftercareAustraliaChildEmergency Service, HospitalEpinephrineHumansPatient DischargeRetrospective StudiesEpinephrineAllergyAnaphylaxisEmergency departmentImmunology

Identifiers

PMID38627619
PMCPMC11022440
OpenAlexW4394868885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.