Evidence map›Paper›PMID 38627285›Full record

ArticleJournal of cancer research and clinical oncology2024

Imaging for local recurrence of breast cancer.

T Schlaiss, L Bott, S-L Herbert, C Bartmann, M Kiesel, J Salmen, S T Sauer, S A Christner, B Petritsch, J-P Grunz and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cancer research and clinical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

T SchlaissDepartment of Gynaecology and Obstetrics, University Hospital Würzburg, Josef-Schneider-Str. 4, 97080, Würzburg, Germany. Schlaiss_T@ukw.de.
L BottDepartment of Gynaecology and Obstetrics, University Hospital Würzburg, Josef-Schneider-Str. 4, 97080, Würzburg, Germany.
S-L HerbertDepartment of Gynaecology and Obstetrics, University Hospital Würzburg, Josef-Schneider-Str. 4, 97080, Würzburg, Germany.
C BartmannDepartment of Gynaecology and Obstetrics, University Hospital Würzburg, Josef-Schneider-Str. 4, 97080, Würzburg, Germany.
M KieselDepartment of Gynaecology and Obstetrics, University Hospital Würzburg, Josef-Schneider-Str. 4, 97080, Würzburg, Germany.
J SalmenDepartment of Gynaecology and Obstetrics, University Hospital Würzburg, Josef-Schneider-Str. 4, 97080, Würzburg, Germany.
S T SauerDepartment of Diagnostic and Interventional Radiology, University Hospital Würzburg, Josef-Schneider-Str. 4, Würzburg, Germany.
S A ChristnerDepartment of Diagnostic and Interventional Radiology, University Hospital Würzburg, Josef-Schneider-Str. 4, Würzburg, Germany.
B PetritschDepartment of Diagnostic and Interventional Radiology, Klinikum Klagenfurt Am Wörthersee, Klagenfurt Am Wörthersee, Austria.
J-P GrunzDepartment of Diagnostic and Interventional Radiology, University Hospital Würzburg, Josef-Schneider-Str. 4, Würzburg, Germany.
A WoeckelDepartment of Gynaecology and Obstetrics, University Hospital Würzburg, Josef-Schneider-Str. 4, 97080, Würzburg, Germany.
S Löb *Department of Gynaecology and Obstetrics, University Hospital Würzburg, Josef-Schneider-Str. 4, 97080, Würzburg, Germany.
J Diessner *Department of Gynaecology and Obstetrics, University Hospital Würzburg, Josef-Schneider-Str. 4, 97080, Würzburg, Germany.
Universitätsklinikum Würzburg · DEKlinikum Klagenfurt · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIsolated locoregional recurrence of breast cancer (ILRR) and contralateral breast cancer (CBC) affect up to 20% of all breast cancer (BC) patients in the first 20 years after primary diagnosis. Treatment options comprise surgical interventions and further systemic therapies depending on the histological subtype. Patients with hereditary breast or ovarian cancer (HBOC) undergo MRI, mammography, and ultrasound in the aftercare of BC, while non-HBOC (nHBOC) patients do not regularly receive MRI. Since early detection is crucial for morbidity and mortality, the evaluation and constant improvement of imaging methods of the breast is necessary.

methodsWe retrospectively analyzed the data of 1499 former BC patients that received imaging of the breast at a tertiary-care university hospital between 2015 and 2020. The analysis comprised various patient characteristics, such as breast density, age, tumor size and subtype, and their influence on BC detection rates by the different imaging methods.

resultsWithin the patient sample, 176 individuals (11.7% of former BC patients) were diagnosed with either ILRR or CBC. CBC was observed in 32.4% of patients, while both ILRR and secondary breast cancer occurred in 20.5% and 23.9% of all patients. Sensitivity of MRI, mammography, and ultrasound for recurrent malignancy was 97.9%, 66.3%, and 67.8%, respectively. ILRR and CBC detection rates were similar for patients with and without HBOC history. Lower breast density and larger tumor size increased the detection rates of all imaging modalities.

conclusionIn breast cancer survivors, MRI might improve the early detection of ILRR and CBC in both HBOC and nHBOC patients.

Indexed as

Breast NeoplasmsFemaleHumansMammographyNeoplasm Recurrence, LocalRetrospective StudiesContralateral breast cancerHereditary breast cancerImaging methodsIsolated locoregional recurrence

Identifiers

PMID38627285
PMCPMC11021243
OpenAlexW4394874188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.