SynthesisNeurosurgical review2024
Local anesthesia with sedation and general anesthesia for the treatment of chronic subdural hematoma: a systematic review and meta-analysis.
Synthesis in Neurosurgical review, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 5 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Comparative outcomes of unilateral and bilateral drainage in bilateral chronic subdural hematoma: A systematic review and meta-analysis.Neurosurgical review · 2026Pooled it
- Updated systematic review of current randomised controlled trials in chronic subdural haematoma.Acta neurochirurgica · 2025Pooled it
- Burr hole evacuation of chronic subdural hematoma in general versus local anesthesia: a systematic review and meta-analysis.Acta neurochirurgica · 2025Pooled it
- Postoperative elevated bed header position versus supine in the management of chronic subdural hematoma: a systematic review and meta-analysis.Acta neurologica Belgica · 2024Pooled it
- Local anesthesia with sedation and general anesthesia for the treatment of chronic subdural hematoma: a systematic review and meta-analysis.Neurosurgical review · 2024Pooled it
- Protected-Airway Local/Regional Analgesia-Dominant Strategy Versus General Anesthesia and ICU Length of Stay in Elderly Patients with Traumatic Intracranial Hemorrhage: A Propensity Score-Matched Cohort Study.Medicina (Kaunas, Lithuania) · 2026Article
- Is There Still a Role for Twist Drill Craniostomy in Contemporary Management of Chronic Subdural Hematoma?Brain sciences · 2026Article
- Age-related tolerability of hard-channel puncture and drainage for chronic subdural hematoma: A single-center retrospective study.Medicine · 2025Observational
- Safety of percutaneous microwave ablation under local anesthesia for uterine fibroids and adenomyosis.Insights into imaging · 2025Article
- Which is better in the management of chronic subdural hematoma: Irrigation, or no irrigation? A systematic review and meta-analysis of randomized controlled trials.Surgical neurology international · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 8 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSurgery is the primary treatment for chronic subdural hematoma, and anesthesia significantly impacts the surgery's outcomes. A previous systematic review compared general anesthesia to local anesthesia in 319 patients. Our study builds upon this research, analyzing 4,367 cases to provide updated and rigorous evidence.
methodsWe systematically searched five electronic databases: PubMed, Cochrane Library, Scopus, Ovid Medline, and Web of Science, to identify eligible comparative studies. All studies published until September 2023 were included in our analysis. We compared six primary outcomes between the two groups using Review Manager Software.
resultsEighteen studies involving a total of 4,367 participants were included in the meta-analysis. The analysis revealed no significant difference between the two techniques in terms of 'recurrence rate' (OR = 0.95, 95% CI [0.78 to 1.15], P = 0.59), 'mortality rate' (OR = 1.02, 95% CI [0.55 to 1.88], P = 0.96), and 'reoperation rate' (OR = 0.95, 95% CI [0.5 to 1.79], P = 0.87). Local anesthesia demonstrated superiority with a lower 'complications rate' than general anesthesia, as the latter had almost 2.4 times higher odds of experiencing complications (OR = 2.4, 95% CI [1.81 to 3.17], P < 0.00001). Additionally, local anesthesia was associated with a shorter 'length of hospital stay' (SMD = 1.19, 95% CI [1.06 to 1.32], P < 0.00001) and a reduced 'duration of surgery' (SMD = 0.94, 95% CI [0.67 to 1.2], P < 0.00001).
conclusionSurgery for chronic subdural hematoma under local anesthesia results in fewer complications, a shorter length of hospital stay, and a shorter duration of the operation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.