Evidence map›Paper›PMID 38626933›Full record

ArticleBMJ open ophthalmology2024

Predictors and long-term patterns of medication adherence to glaucoma treatment in Denmark-an observational registry study of 30 100 Danish patients with glaucoma.

Miriam Kolko, Rikke Faergemann Hansen, Louise G Dal, Emma Sabelström, Magnus Brandel, Andreas Hoiberg Bentsen, Anne Cathrine Falch-Joergensen

Abstract read
In one paragraph

Article in BMJ open ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miriam KolkoDepartment of Drug Design and Pharmacology, University of Copenhagen Faculty of Health Sciences, Copenhagen, Denmark.ORCID 0000-0001-8697-0734
Rikke Faergemann HansenReal World Evidence, Signum Life Science, Copenhagen, Denmark.ORCID 0009-0007-0480-7249
Louise G DalAbbVie A/S, Copenhagen, Denmark.ORCID 0009-0007-3133-9161
Emma SabelströmAbbVie A/S, Copenhagen, Denmark.
Magnus BrandelAbbVie A/S, Copenhagen, Denmark.
Andreas Hoiberg BentsenReal World Evidence, Signum Life Science, Copenhagen, Denmark.ORCID 0000-0002-0504-2598
Anne Cathrine Falch-JoergensenReal World Evidence, Signum Life Science, Copenhagen, Denmark acfj@signumlifescience.com.ORCID 0000-0002-8845-4204

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSelf-treatment with glaucoma medication (eye drops) has been associated with adherence challenges. Poor adherence results in worse outcomes in terms of visual field loss.

objectiveTo investigate patterns in medication adherence among Danish patients with glaucoma in relation to selected predictors of adherence, long-term adherence patterns, and long-term societal economic consequences of poor adherence. METHODS AND ANALYSIS: This register-based study included 30 100 glaucoma patients followed for 10 years between 2000 and 2018. Glaucoma was identified from the Danish national registers by diagnosis of Open Angle Glaucoma and/or by redeemed prescriptions of glaucoma medication. Logistic regression models were applied to estimate patient characteristics related to medical adherence. Diagnosis-related group fees were applied to estimate healthcare costs.

resultsHigh adherence in the first year(s) of treatment was less likely among men (OR

conclusionIncreasing age, female sex and low comorbidity score are correlated with better adherence to glaucoma treatment. Adherence in the first years of treatment may be a good predictor for future adherence. In the long term, patients with poor adherence are overall more expensive to society in terms of hospital contacts.

Indexed as

GlaucomaGlaucoma, Open-AngleDenmarkFemaleHumansMaleMedication AdherenceRegistriesEpidemiologyGlaucomaPublic healthTreatment Medical

Identifiers

PMID38626933
PMCPMC11029215

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.