Evidence map›Paper›PMID 38626728›Full record

ArticleUrologia internationalis2024

Ureterorenoscopic Stone Removal without Antibiotic Prophylaxis.

Maximilian Reinhard Müller, Eva-Maria Prey, Philipp Julian Spachmann, Christopher Goßler, Maximilian Burger, Marco Julius Schnabel

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Urologia internationalis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Maximilian Reinhard MüllerDepartment of Urology, University of Regensburg, Caritas St. Josef Medical Center, Regensburg, Germany.
Eva-Maria PreyDepartment of Urology, University of Regensburg, Caritas St. Josef Medical Center, Regensburg, Germany.
Philipp Julian SpachmannOutpatient Department for Urology, Landau an der Isar, Germany.
Christopher GoßlerDepartment of Urology, University of Regensburg, Caritas St. Josef Medical Center, Regensburg, Germany.
Maximilian BurgerDepartment of Urology, University of Regensburg, Caritas St. Josef Medical Center, Regensburg, Germany.
Marco Julius SchnabelDepartment of Urology, University of Regensburg, Caritas St. Josef Medical Center, Regensburg, Germany.
University of Regensburg · DEUniversity of Koblenz and Landau · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this study was to assess the feasibility of sparing routine antibiotic prophylaxis in patients without preoperative urinary tract infection undergoing ureterorenoscopy (URS) for stone removal.

methodsA retrospective, monocentric study was conducted to evaluate the outcome of a modified perioperative antibiotic management strategy according to the principles of antibiotic stewardship. Patients with preoperative unremarkable urine culture received no antibiotic prophylaxis for URS stone removal (NoPAP). The NoPAP group was compared to a historic URS cohort, when antibiotic prophylaxis (PAP) was standard of care. Analysis focused on postoperative complications.

resultsPostoperative fever occurred in 1% of the NoPAP and 2% of the PAP patients (p = 0.589). Clavien 1-3 complications did not differ between groups with 9% in the NoPAP and 6.2% in the PAP (p = 0.159). No Clavien 4-5 complications were seen. We identified a residual stone (p = 0.033) and an ASA score 3-4 (p = 0.004) as significant risk factors for postoperative fever. By sparing routine antibiotic prophylaxis, the overall antibiotic usage was reduced from 100% (PAP) to 8.3% (NoPAP).

conclusionSparing a routine antibiotic prophylaxis during URS for stone removal seems feasible in patients with unremarkable preoperative urine culture for most of the patients. A prospective validation is warranted.

Indexed as

Antibiotic ProphylaxisFeasibility StudiesKidney CalculiUreteroscopyAdultAgedAnti-Bacterial AgentsFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesTreatment OutcomeUrinary Tract InfectionsAnti-Bacterial AgentsAntibiotic prophylaxisAntibiotic stewardshipKidney stoneUreteric stoneUreterorenoscopyUrinary tract infectionUrolithiasis

Identifiers

PMID38626728
PMCPMC11449176
OpenAlexW4394840514

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.