ArticleAmerican journal of respiratory and critical care medicine2024
Disrupted BMP-9 Signaling Impairs Pulmonary Vascular Integrity in Hepatopulmonary Syndrome.
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In one paragraph
Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
8.9field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- International Liver Transplantation Society practice guideline update on portopulmonary hypertension.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2026Guideline
- Precision inflammation targeting via myeloperoxidase mediated antioxidant melanin nanomedicines for chronic inflammation therapy.Nature communications · 2026Article
- Article
- Activin Signaling Inhibitors in Pulmonary Hypertension: A State-of-the-Art Review.Pulmonary circulation · 2026Review
- Advances in the pathogenesis and clinical management of pulmonary hypertension.Medical review (2021) · 2026Review
- The Importance of Liver-Lung Communication in Pulmonary Vascular Diseases.Comprehensive Physiology · 2026Review
- Sotatercept for the treatment of portopulmonary hypertension: a case report.Communications medicine · 2026Article
- TGF-β/BMP signaling in skeletal biology: molecular mechanisms, regulatory networks, and therapeutic implications in development, regeneration, and disease.Bone research · 2026Review
- Liver transplantation for hepatopulmonary syndrome: A systematic review and meta-analysis.JHEP reports : innovation in hepatology · 2026Article
- Transpulmonary Proteome Gradients Identify Pathways Involved in Pulmonary Vascular Disease Due To Heart Failure.Circulation. Heart failure · 2025Observational
- A Tale of Two Organs: The Liver-Lung Axis in Pulmonary Disease.Comprehensive Physiology · 2025Article
- Sotatercept in pulmonary arterial hypertension: revolution, risk and the road ahead.The European respiratory journal · 2025Article
- BMP9 regulates the endothelial secretome to drive pulmonary hypertension.bioRxiv : the preprint server for biology · 2025Article
- Bone morphogenetic protein-9 controls pulmonary vascular growth and remodeling.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Disruption of Hepatic Sinusoidal Homeostasis Leads to Hepatopulmonary Syndrome.Journal of cellular and molecular medicine · 2025Review
- Predictive models and clinical manifestations of intrapulmonary vascular dilatation and hepatopulmonary syndrome in patients with cirrhosis: Prospective comparative study.World journal of gastroenterology · 2025Article
- Observational
- Placental growth factor modulates endothelial NO production and exacerbates experimental hepatopulmonary syndrome.JHEP reports : innovation in hepatology · 2025Article
- Pathology and pathobiology of pulmonary hypertension: current insights and future directions.The European respiratory journal · 2024Review
- Genetics and precision genomics approaches to pulmonary hypertension.The European respiratory journal · 2024Review
Corrections and comments
- Commented on by
Authors and funding
21 authors at 3 institutions in 1 country.
Fabien RobertUniversité Paris-Saclay, Unité Mixte de Recherche en Santé (UMR_S) 999 "Hypertension Pulmonaire: Physiopathologie et Innovation Thérapeutique (HPPIT)", Le Kremlin-Bicêtre, France.ORCID 0000-0003-3132-8706
Marie-Caroline CertainUniversité Paris-Saclay, Unité Mixte de Recherche en Santé (UMR_S) 999 "Hypertension Pulmonaire: Physiopathologie et Innovation Thérapeutique (HPPIT)", Le Kremlin-Bicêtre, France.
Audrey BaronUniversité Paris-Saclay, Unité Mixte de Recherche en Santé (UMR_S) 999 "Hypertension Pulmonaire: Physiopathologie et Innovation Thérapeutique (HPPIT)", Le Kremlin-Bicêtre, France.
Raphaël ThuilletUniversité Paris-Saclay, Unité Mixte de Recherche en Santé (UMR_S) 999 "Hypertension Pulmonaire: Physiopathologie et Innovation Thérapeutique (HPPIT)", Le Kremlin-Bicêtre, France.
Léa DuhautCentre Hépato-Biliaire, AP-HP, Hôpital Paul Brousse, Villejuif, France.
Mina OttavianiUniversité Paris-Saclay, Unité Mixte de Recherche en Santé (UMR_S) 999 "Hypertension Pulmonaire: Physiopathologie et Innovation Thérapeutique (HPPIT)", Le Kremlin-Bicêtre, France.
Mustapha Kamel ChelghamUniversité Paris-Saclay, Unité Mixte de Recherche en Santé (UMR_S) 999 "Hypertension Pulmonaire: Physiopathologie et Innovation Thérapeutique (HPPIT)", Le Kremlin-Bicêtre, France.
Corinne NormandUniversité Paris-Saclay, Unité Mixte de Recherche en Santé (UMR_S) 999 "Hypertension Pulmonaire: Physiopathologie et Innovation Thérapeutique (HPPIT)", Le Kremlin-Bicêtre, France.
Nihel BerrebehUniversité Paris-Saclay, Unité Mixte de Recherche en Santé (UMR_S) 999 "Hypertension Pulmonaire: Physiopathologie et Innovation Thérapeutique (HPPIT)", Le Kremlin-Bicêtre, France.
Nicolas RicardBiosanté Unit UMR_S 1292, Grenoble Alpes University, INSERM, Commissariat à l'énergie atomique et aux énergies alternative (CEA), Grenoble, France.
Valerie FurlanService de pharmacologie-toxicologie, AP-HP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Agnès Desroches-CastanBiosanté Unit UMR_S 1292, Grenoble Alpes University, INSERM, Commissariat à l'énergie atomique et aux énergies alternative (CEA), Grenoble, France.
Emmanuel GonzalesUniversité Paris-Saclay, INSERM, UMR_S 1193, Hepatinov, Orsay, France.
Emmanuel JacqueminUniversité Paris-Saclay, INSERM, UMR_S 1193, Hepatinov, Orsay, France.
Olivier SitbonUniversité Paris-Saclay, Unité Mixte de Recherche en Santé (UMR_S) 999 "Hypertension Pulmonaire: Physiopathologie et Innovation Thérapeutique (HPPIT)", Le Kremlin-Bicêtre, France.ORCID 0000-0002-1942-1951
Marc HumbertUniversité Paris-Saclay, Unité Mixte de Recherche en Santé (UMR_S) 999 "Hypertension Pulmonaire: Physiopathologie et Innovation Thérapeutique (HPPIT)", Le Kremlin-Bicêtre, France.
Sabine BaillyBiosanté Unit UMR_S 1292, Grenoble Alpes University, INSERM, Commissariat à l'énergie atomique et aux énergies alternative (CEA), Grenoble, France.
Audrey CoillyCentre Hépato-Biliaire, AP-HP, Hôpital Paul Brousse, Villejuif, France.
Christophe GuignabertUniversité Paris-Saclay, Unité Mixte de Recherche en Santé (UMR_S) 999 "Hypertension Pulmonaire: Physiopathologie et Innovation Thérapeutique (HPPIT)", Le Kremlin-Bicêtre, France.ORCID 0000-0002-8545-4452
Ly TuUniversité Paris-Saclay, Unité Mixte de Recherche en Santé (UMR_S) 999 "Hypertension Pulmonaire: Physiopathologie et Innovation Thérapeutique (HPPIT)", Le Kremlin-Bicêtre, France.
Laurent SavaleUniversité Paris-Saclay, Unité Mixte de Recherche en Santé (UMR_S) 999 "Hypertension Pulmonaire: Physiopathologie et Innovation Thérapeutique (HPPIT)", Le Kremlin-Bicêtre, France.ORCID 0000-0002-6862-8975
Inserm · FRUniversité Paris-Sud · FRAssistance Publique – Hôpitaux de Paris · FR
Funding
Agence Nationale de la RechercheChancellerie des Universités (Legs Poix)Fondation du SouffleFondation pour la Recherche MédicaleInserm TransfertUniversité Paris Saclay
Abstract
PubMed holds no abstract for this paper.
Indexed as
Disease Models, AnimalGrowth Differentiation Factor 2Hepatopulmonary SyndromeAdultAgedAnimalsCase-Control StudiesFemaleHumansHypertension, PortalLiver CirrhosisLungMaleMiddle AgedRatsSignal TransductionBmp9 protein, ratGrowth Differentiation Factor 2TacrolimusBMP-9cirrhosishepatopulmonary syndromeintrapulmonary vascular dilatationsportal hypertension
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.