Evidence map›Paper›PMID 38625814›Full record

ArticleAngewandte Chemie (International ed. in English)2024

Selective Arylation of RNA 2'-OH Groups via S

Sayantan Chatterjee, Lu Xiao, Wenrui Zhong, Sheng Feng, Eric T Kool

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Site-Selective Ligand Selection by Mutational Profiling for Covalent RNA Targeting.Angewandte Chemie (International ed. in English) · 2026
    Article
  3. Fluorogenic Covalent Probes for RNA.Journal of the American Chemical Society · 2025
    Article
  4. Sequence-Specific Installation of Aryl Groups in RNA via DNA-Catalyst Conjugates.Angewandte Chemie (International ed. in English) · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sayantan ChatterjeeDepartment of Chemistry, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0001-9265-595X
Lu XiaoDepartment of Chemistry, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0003-1934-4711
Wenrui ZhongDepartment of Chemistry, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-1236-0842
Sheng FengDepartment of Chemistry, Stanford University, Stanford, CA 94305, USA.
Eric T KoolDepartment of Chemistry, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-7310-2935
Stanford University · US

Funding

Transcriptome Analysis with RNA-Reactive ProbesR35GM145357 · NIGMS · STANFORD UNIVERSITY · PI ERIC T. KOOL · 2022 to 2026
$3.0M
Foundation for the National Institutes of Health GM145375Jane Coffin Childs Memorial Fund for Medical ResearchNIGMS NIH HHS R35 GM145357
6 · The paper itself

Abstract

Small-molecule reactions at the 2'-OH groups of RNA enable useful applications for transcriptome technology and biology. To date, all reactions have involved carbonyl acylation and mechanistically related sulfonylation, limiting the types of modifications and properties that can be achieved. Here we report that electron-deficient heteroaryl species selectively react with 2'-OH groups of RNA in water via S

Indexed as

RNAAmmonium CompoundsHeterocyclic CompoundsMolecular StructureQuaternary Ammonium CompoundsTriazinesAmmonium CompoundsHeterocyclic CompoundsQuaternary Ammonium CompoundsRNATriazinesArylationLabelingRNA reactionSelectivityTriazine

Identifiers

PMID38625814
PMCPMC11905364
OpenAlexW4394856311

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.