ArticleInternational urology and nephrology2024
Association between atherogenic indexes and erectile dysfunction: a cross-sectional analysis of the National Health and Nutrition Examination Survey 2001-2004.
Article in International urology and nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- The relationship between atherogenic index of plasma and erectile dysfunction: a cross-sectional observational study.World journal of urology · 2026Observational
- Correlation between Castelli risk index-I and female infertility: A cross-sectional study.Lipids in health and disease · 2025Article
- Association between five novel anthropometric indices and erectile dysfunction in US adults from NHANES database.Scientific reports · 2025Article
- Inverse association between atherogenic index of plasma and testosterone in US adult males: A large cross-sectional study from the NAHNES 2011-2016.Frontiers in physiology · 2025Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
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Abstract
purposeElevated blood lipids are considered a risk factor for atherosclerosis, which can lead to erectile dysfunction. This study aimed to explore the relationship between the atherogenic index of plasma (AIP), atherogenic coefficient (AC), Castelli's risk index-I (CRI-I), Castelli's risk index-II (CRI-II), and erectile dysfunction.
methodsBased on the National Health and Nutrition Examination Survey (NHANES) data from 2001-2004, multivariable-adjusted logistic regression models were used to evaluate the association between AIP, AC, CRI-I, and CRI-II with ED. Smooth curve fitting was employed to assess the linear association.
resultsA total of 1806 male participants with complete data were enrolled in the study. In Model 1, those in the highest tertile of AIP had a 49% increased risk of ED compared to the lowest tertile (OR 1.49; 95% CI 1.15-1.91 p = 0.0021). After adjusting for the variables of age, race, education, body mass index, and poverty income ratio (PIR), significant positive correlations were found between ED and AIP, with each 1-unit increase in AIP associated with a 65% increase in the risk of developing ED (OR 1.65; 95% CI 1.03-2.64 p = 0.0361).
conclusionsAIP is positively associated with the development of ED in US adults. More prospective cohort studies are needed to confirm the link between AIP and ED.
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