Evidence map›Paper›PMID 38625565›Full record

ArticleArchives of microbiology2024

A sulfated exopolysaccharide derived from Chlorella sp. exhibiting in vitro anti-α-D-Glucosidase activity.

Karima Guehaz, Zakaria Boual, Alia Telli, Hicham Meskher, Hakim Belkhalfa, Guillaume Pierre, Philippe Michaud, Alessandra Adessi

Abstract read
In one paragraph

Article in Archives of microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Karima GuehazLaboratory for the Protection of Ecosystems in Arid and Semi-Arid Zones, FNSV, Kasdi Merbah University, 30000, Ouargla, Algeria. gagakarima@gmail.com.
Zakaria BoualLaboratory for the Protection of Ecosystems in Arid and Semi-Arid Zones, FNSV, Kasdi Merbah University, 30000, Ouargla, Algeria.
Alia TelliLaboratory for the Protection of Ecosystems in Arid and Semi-Arid Zones, FNSV, Kasdi Merbah University, 30000, Ouargla, Algeria.
Hicham MeskherDivision of Process Engineering, College of Science and Technology, Chadli Bendjedid University, 36000, El Tarf, Algeria.
Hakim BelkhalfaScientific and Technical Research Center in Physicochemical Analysis, 30000, Ouargla, Algeria.
Guillaume PierreInstitut Pascal, Université Clermont Auvergne, CNRS, Clermont Auvergne INP, 63000, Clermont-Ferrand, France.
Philippe MichaudInstitut Pascal, Université Clermont Auvergne, CNRS, Clermont Auvergne INP, 63000, Clermont-Ferrand, France.
Alessandra AdessiDepartment of Agriculture Food Environment and Forestry (DAGRI), University of Florence, 50144, Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a great scientific curiosity to discover all environments sheltering microalgae, especially those with exceptional characteristics from coldest to hottest ones, the purpose remains to explore the potential of the native microalgae flora and the research for new bioactive compounds. This study aimed to isolate a polysaccharide-producing microalga from an extreme ecosystem and to evaluate its capacity to inhibit the α-D-glucosidase enzyme. Chlorella strain is isolated from hypersaline Lake in the Algerian desert. The exopolysaccharide extraction was performed by the concentration of free-cell supernatant in a rotary evaporator. The infrared analysis showed a characteristic footprint of carbohydrates with particular functional groups, such as sulfate. Gas chromatography-mass spectrometry has revealed a hetero-exopolysaccharide composed of galactose 35.75%, glucose 21.13%, xylose 16.81%, fructose 6.96%, arabinose 5.10%, and glucuronic acid 2.68%. The evaluation of the anti-hyperglycemic activity demonstrated a significant α-D-glucosidase inhibition of 80.94 ± 0.01% at 10 mg mL

Indexed as

ChlorellaSulfatesArabinoseEcosystemGlucosidasesArabinoseGlucosidasesSulfatesChlorella sp.ExopolysaccharideSalt lakeα- d -Glucosidase inhibition

Identifiers

PMID38625565
PMCPMC11021272

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.