Evidence map›Paper›PMID 38625482›Full record

ArticleJournal of general internal medicine2024

Impact of SARS-CoV-2 Infection on Long-Term Depression Symptoms among Veterans.

Jason I Chen, David Bui, Theodore J Iwashyna, Troy A Shahoumian, Alex Hickok, Megan Shepherd-Banigan, Eric J Hawkins, Jennifer Naylor, Diana J Govier, Thomas F Osborne and 10 more

Erratum issued Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of general internal medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05394025 (COVID-19 Observational Research Collaboratory - Long-Term Outcomes), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05394025 completednot on this map

COVID-19 Observational Research Collaboratory - Long-Term Outcomes (LTO) Study

TypeobservationalSponsorVA Office of Research and DevelopmentRan2022 to 2024Enrolled479ConditionsCOVID-19, SARS-CoV-2 Infection
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 11 institutions in 1 country.

Jason I ChenCenter to Improve Veteran Involvement in Care (CIVIC), VA Portland Health Care System (HCS), Portland, OR, USA. Jason.Chen1@va.gov.ORCID 0000-0001-6490-164X
David BuiCenter to Improve Veteran Involvement in Care (CIVIC), VA Portland Health Care System (HCS), Portland, OR, USA.
Theodore J IwashynaDepartments of Medicine and Health Policy and Management, Johns Hopkins University, Baltimore, MD, USA.
Troy A ShahoumianVHA, Patient Care Services: Health Solutions, Washington, DC, USA.
Alex HickokCenter to Improve Veteran Involvement in Care (CIVIC), VA Portland Health Care System (HCS), Portland, OR, USA.
Megan Shepherd-BaniganCenter of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham VA HCS, Durham, NC, USA.
Eric J HawkinsCenter of Innovation for Veteran-Centered and Value-Driven Care, VA Puget Sound HCS, Seattle, WA, USA.
Jennifer NaylorSchool of Medicine, Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA.
Diana J GovierCenter to Improve Veteran Involvement in Care (CIVIC), VA Portland Health Care System (HCS), Portland, OR, USA.
Thomas F OsborneVA Palo Alto HCS, Palo Alto, CA, USA.
Valerie A SmithCenter of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham VA HCS, Durham, NC, USA.
C Barrett BowlingCenter of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham VA HCS, Durham, NC, USA.
Edward J BoykoSeattle Epidemiologic Research Information Center, VA Puget Sound HCS, Seattle, WA, USA.
George N IoannouCenter of Innovation for Veteran-Centered and Value-Driven Care, VA Puget Sound HCS, Seattle, WA, USA.
Matthew L MaciejewskiCenter of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham VA HCS, Durham, NC, USA.
Ann M O'HareCenter of Innovation for Veteran-Centered and Value-Driven Care, VA Puget Sound HCS, Seattle, WA, USA.
Elizabeth M VigliantiCenter for Clinical Management Research, VA Ann Arbor HCS, Ann Arbor, MI, USA.
Amy S-B BohnertCenter for Clinical Management Research, VA Ann Arbor HCS, Ann Arbor, MI, USA.
Denise M HynesCenter to Improve Veteran Involvement in Care (CIVIC), VA Portland Health Care System (HCS), Portland, OR, USA.
V. A. HSRDSARS-C.O.V.-2 Observational Research Collaboratory (CORC)
Duke University · USUniversity of Washington · USUniversity of Michigan · USVA Portland Health Care System · USJohns Hopkins University · USOffice of Patient Care Services · USOregon Health & Science University · USOregon State University · USPortland State University · USUniversity of Puget Sound · USVA Palo Alto Health Care System · US

Funding

HSR&D Senior Research Career Scientist AwardIK6HX003395 · VA · PORTLAND VA MEDICAL CENTER · PI Denise M. Hynes · 2021 to 2026
–
Health Services Research and Development C19-21-278Health Services Research and Development C19-21-279Health Services Research and Development CDA 18-185HSRD VA IK6 HX003395
6 · The paper itself

Abstract

backgroundPrior research demonstrates that SARS-COV-2 infection can be associated with a broad range of mental health outcomes including depression symptoms. Veterans, in particular, may be at elevated risk of increased depression following SARS-COV-2 infection given their high rates of pre-existing mental and physical health comorbidities. However, few studies have tried to isolate SARS-COV-2 infection associations with long term, patient-reported depression symptoms from other factors (e.g., physical health comorbidities, pandemic-related stress).

objectiveTo evaluate the association between SARS-COV-2 infection and subsequent depression symptoms among United States Military Veterans.

designSurvey-based non-randomized cohort study with matched comparators.

participantsA matched-dyadic sample from a larger, stratified random sample of participants with and without known to SARS-COV-2 infection were invited to participate in a survey evaluating mental health and wellness 18-months after their index infection date. Sampled participants were stratified by infection severity of the participant infected with SARS-COV-2 (hospitalized or not) and by month of index date. A total of 186 participants in each group agreed to participate in the survey and had sufficient data for inclusion in analyses. Those in the uninfected group who were later infected were excluded from analyses. MAIN MEASURES: Participants were administered the Patient Health Questionnaire-9 as part of a phone interview survey. Demographics, physical and mental health comorbidities were extracted from VHA administrative data. KEY

resultsVeterans infected with SARS-COV-2 had significantly higher depression symptoms scores compared with those uninfected. In particular, psychological symptoms (e.g., low mood, suicidal ideation) scores were elevated relative to the comparator group (M

conclusionSARS-COV-2 infection was associated with more depression symptoms among Veterans at 18-months post-infection. Routine evaluation of depression symptoms over time following SARS-COV-2 infection is important to facilitate adequate assessment and treatment.

Indexed as

COVID-19DepressionVeteransAdultAgedCohort StudiesFemaleHumansMaleMiddle AgedSARS-CoV-2United States

Identifiers

PMID38625482
PMCPMC11169300
OpenAlexW4394853614

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.