Evidence map›Paper›PMID 38625414›Full record

ArticleCellular and molecular neurobiology2024

TIMP-3 Alleviates White Matter Injury After Subarachnoid Hemorrhage in Mice by Promoting Oligodendrocyte Precursor Cell Maturation.

Peiwen Guo, Xufang Ru, Jiru Zhou, Mao Chen, Yanling Li, Mingxu Duan, Yuanshu Li, Wenyan Li, Yujie Chen, Shilun Zuo and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Peiwen Guo *Department of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.
Xufang Ru *Department of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.
Jiru ZhouDepartment of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.
Mao ChenDepartment of Neurology, Xinqiao Hospital, Third Military Medical University (Army Medical University), 83 Xinqiao Main Street, Shapingba District, Chongqing, 400037, China.
Yanling LiDepartment of Neurology, Xinqiao Hospital, Third Military Medical University (Army Medical University), 83 Xinqiao Main Street, Shapingba District, Chongqing, 400037, China.
Mingxu DuanDepartment of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.
Yuanshu LiDepartment of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.
Wenyan LiDepartment of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.
Yujie ChenDepartment of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China. chenyj@tmmu.edu.cn.ORCID http://orcid.org/0000-0002-9905-9138
Shilun ZuoDepartment of Neurology, Xinqiao Hospital, Third Military Medical University (Army Medical University), 83 Xinqiao Main Street, Shapingba District, Chongqing, 400037, China. shilunzuo@tmmu.edu.cn.ORCID http://orcid.org/0000-0002-7401-5681
Hua FengDepartment of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.
Army Medical University · CN

Funding

National Natural Science Foundation of China 82030036National Natural Science Foundation of China 82371333Natural Science Foundation Project of Chongqing, Chongqing Science and Technology Commission cstc2019jcyj-msxmX0535Young PhD Talents Cultivation Project of Xinqiao Hospital 2022YQB069
6 · The paper itself

Abstract

Subarachnoid hemorrhage (SAH) is associated with high mortality and disability rates, and secondary white matter injury is an important cause of poor prognosis. However, whether brain capillary pericytes can directly affect the differentiation and maturation of oligodendrocyte precursor cells (OPCs) and subsequently affect white matter injury repair has still been revealed. This study was designed to investigate the effect of tissue inhibitor of metalloproteinase-3 (TIMP-3) for OPC differentiation and maturation. PDGFRβ

Indexed as

Oligodendrocyte Precursor CellsSubarachnoid HemorrhageWhite MatterAnimalsBrainMaleMiceTissue Inhibitor of Metalloproteinase-3Timp3 protein, mouseTissue Inhibitor of Metalloproteinase-3Oligodendrocyte precursor cellPericyteSubarachnoid hemorrhageTissue inhibitor of metalloproteinase-3White matter

Identifiers

PMID38625414
PMCPMC11021342
OpenAlexW4394846351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.