Evidence map›Paper›PMID 38624231›Full record

ArticleJournal of virology2024

NS7a of SADS-CoV promotes viral infection via inducing apoptosis to suppress type III interferon production.

Xiaowei Wang, Wenjing Qiu, Guangli Hu, Xiaoyuan Diao, Yunfei Li, Yue Li, Peng Li, Yufang Liu, Yongtong Feng, Chunyi Xue and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Xiaowei WangState Key Laboratory of Biocontrol, School of Life Science, Sun Yat-sen University, Guangzhou, China.
Wenjing QiuState Key Laboratory of Biocontrol, School of Life Science, Sun Yat-sen University, Guangzhou, China.
Guangli HuState Key Laboratory of Biocontrol, School of Life Science, Sun Yat-sen University, Guangzhou, China.
Xiaoyuan DiaoState Key Laboratory of Biocontrol, School of Life Science, Sun Yat-sen University, Guangzhou, China.
Yunfei LiState Key Laboratory of Biocontrol, School of Life Science, Sun Yat-sen University, Guangzhou, China.
Yue LiState Key Laboratory of Biocontrol, School of Life Science, Sun Yat-sen University, Guangzhou, China.
Peng LiVeterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, USA.
Yufang LiuState Key Laboratory of Biocontrol, School of Life Science, Sun Yat-sen University, Guangzhou, China.
Yongtong FengState Key Laboratory of Biocontrol, School of Life Science, Sun Yat-sen University, Guangzhou, China.
Chunyi XueState Key Laboratory of Biocontrol, School of Life Science, Sun Yat-sen University, Guangzhou, China.
Yongchang CaoState Key Laboratory of Biocontrol, School of Life Science, Sun Yat-sen University, Guangzhou, China.
Zhichao XuState Key Laboratory of Biocontrol, School of Life Science, Sun Yat-sen University, Guangzhou, China.ORCID 0009-0009-1193-374X
Sun Yat-sen University · CNIowa State University · US

Funding

GDSTC | Natural Science Foundation of Guangdong Province 2021A1515011276MOST | National Key Research and Development Program of China (NKPs) 2021YFD1801101MOST | National Natural Science Foundation of China (NSFC) 31902248The special fund for biosecurity technology of Guangdong province 2022B1111030001
6 · The paper itself

Abstract

Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a newly discovered swine coronavirus with potential cross-species transmission risk. Although SADS-CoV-induced host cell apoptosis and innate immunity antagonization has been revealed, underlying signaling pathways remain obscure. Here, we demonstrated that infection of SADS-CoV induced apoptosis

Indexed as

ApoptosisImmunity, InnateInterferon Regulatory Factor-3InterferonsViral Nonstructural ProteinsAlphacoronavirusAnimalsCaspase 3Chlorocebus aethiopsCoronavirus InfectionsHEK293 CellsHumansInterferon LambdaSignal TransductionSwineSwine DiseasesCaspase 3Interferon LambdaInterferon Regulatory Factor-3InterferonsViral Nonstructural Proteinsapoptosisapoptosis inducing factor mitochondria associated 1 (AIFM1)IFN-λNS7aSwine acute diarrhea syndrome virus (SADS-CoV)viral replication

Identifiers

PMID38624231
PMCPMC11092342
OpenAlexW4394844743

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.