Evidence map›Paper›PMID 38624207›Full record

ArticlemBio2024

Fluoride export is required for the competitive fitness of pathogenic microorganisms in dental biofilm models.

Aditya Banerjee, Chia-Yu Kang, Minjun An, B Ben Koff, Sham Sunder, Anuj Kumar, Livia M A Tenuta, Randy B Stockbridge

Open access · goldAbstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Adaptive evolution ofJournal of bacteriology · 2026
    Article
  3. Article
  4. Fluoride triggers lysis inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Aditya BanerjeeDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-0365-5582
Chia-Yu KangProgram in Biophysics, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0001-5744-3820
Minjun AnDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0009-0005-0510-169X
B Ben KoffDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.
Sham SunderDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.
Anuj KumarDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.
Livia M A TenutaSchool of Dentistry, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-4626-4477
Randy B StockbridgeDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0001-8848-3032
University of Michigan · US

Funding

Adhesin Amyloid BiologyR21AI178229 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GESTWICKI, JASON E, KUMAR, ANUJ · 2023 to 2024
$432k
Potentiation of fluoride toxicity in oral pathogensR21DE032837 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ANDALO-TENUTA, LIVIA MARIA, STOCKBRIDGE, RANDY B. · 2023 to 2024
$429k
Isolating the phenotypic effects of individual loss of heterozygosity events in a pathogenic yeast model systemR21AI168571 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JAMES, TIM, KUMAR, ANUJ · 2022 to 2023
$421k
NIAID NIH HHS R21 AI168571NIAID NIH HHS R21 AI178229NIDCR NIH HHS R21 DE032837
6 · The paper itself

Abstract

Microorganisms resist fluoride toxicity using fluoride export proteins from one of several different molecular families. Cariogenic species IMPORTANCE: Dental caries is a globally prevalent condition that occurs when pathogenic species, including

Indexed as

BiofilmsCandida albicansFluoridesStreptococcus gordoniiStreptococcus mutansBacterial ProteinsDental CariesGene Knockout TechniquesBacterial ProteinsFluoridesbiofilmscariesCLCcrcBdentalFlucfluoridetransporter

Identifiers

PMID38624207
PMCPMC11077948
OpenAlexW4394853628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.