Evidence map›Paper›PMID 38624072›Full record

ArticleCartilage2025

Faster Bone Gap Union in Medial Opening Wedge High Tibial Osteotomy With 3D-Printed Synthetic Bioresorbable Polycaprolactone and Tricalcium Phosphate Osteotomy Gap Fillers Compared to Allogeneic Osteotomy Gap Fillers: A Retrospective Matched-Pair Cohort Study.

Shaun Kai Kiat Chua, Walter-Soon-Yaw Wong, Don Thong Siang Koh, Rehena Sultana, Junwei Soong, Kong Hwee Lee, Hamid Rahmatullah Bin Abd Razak

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Cartilage, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
  3. [Research progress in biomechanics of different fixation methods for medial opening-wedge high tibial osteotomy].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Shaun Kai Kiat ChuaMinistry of Health, Singapore.ORCID 0000-0003-0995-4858
Walter-Soon-Yaw WongDepartment of Orthopaedic Surgery, Sengkang General Hospital, Singapore.
Don Thong Siang KohDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore.
Rehena SultanaDuke-National University of Singapore Medical School, Singapore.
Junwei SoongDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore.
Kong Hwee LeeDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore.
Hamid Rahmatullah Bin Abd RazakDepartment of Orthopaedic Surgery, Sengkang General Hospital, Singapore.
Singapore General Hospital · SGMinistry of Health · SGNational University of Singapore · SGSengkang General Hospital · SGSingHealth · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe use of synthetic bone substitute material (BSM) as osteotomy gap fillers have been reported to improve outcomes in medial opening wedge high tibial osteotomy (MOWHTO). This study aims to evaluate the early radiological outcomes (bone union) and complication rates of the novel patient-specific 3D-printed honeycomb-structured polycaprolactone and tricalcium phosphate (PCL-TCP) synthetic graft compared to allogeneic bone grafts as an osteotomy gap filler in MOWHTO.

methodsA retrospective matched-pair analysis of patients who underwent MOWHTO with either PCL-TCP synthetic graft or allogenic femoral head allograft as osteotomy gap filler was performed. The osteotomy gap was split into equal zones (Zone 1-5), and bone union was evaluated on anteroposterior radiographs based on the van Hemert classification at 1, 3, 6, and 12 months postoperatively. Postoperative complications including infection, lateral hinge fractures, and persistent pain was measured. The study and control group were matched for age, smoking status, diabetes mellitus, and osteotomy gap size.

resultsSignificantly greater bone union progression was observed in the PCL-TCP group than in the allograft group at 1 month (Zones 1-3), 3 months (Zones 1-4), 6 months (Zones 1-2, 4), and 12 months (Zones 2-3, 5) postoperatively (

conclusionsBone union rates observed in patients who underwent MOWHTO with the PCL-TCP synthetic graft osteotomy gap filler were superior to those in the allograft group at 1 year postoperatively, with no significant difference in complication rates (postoperative infection, lateral hinge fractures, and persistent pain).

Indexed as

Bone SubstitutesBone TransplantationCalcium PhosphatesOsteotomyPolyestersTibiaAbsorbable ImplantsAdultAgedFemaleHumansMaleMatched-Pair AnalysisMiddle AgedPostoperative ComplicationsPrinting, Three-DimensionalBone SubstitutesCalcium PhosphatespolycaprolactonePolyesterstricalcium phosphate3D-printingallograftbone unionmedial opening wedge high tibialosteotomypolycaprolactone and tricalcium phosphate

Identifiers

PMID38624072
PMCPMC11569676
OpenAlexW4394844406

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.