Evidence map›Paper›PMID 38623995›Full record

ArticleFuture medicinal chemistry2024

Key structural requirements of benzamide derivatives for histone deacetylase inhibition: design, synthesis and biological evaluation.

Narges Cheshmazar, Maryam Hamzeh-Mivehroud, Salar Hemmati, Hoda Abolhasani, Fatemeh Heidari, Hojjatollah Nozad Charoudeh, Matthes Zessin, Mike Schutkowski, Wolfgang Sippl, Siavoush Dastmalchi

Open access · greenAbstract read
In one paragraph

Article in Future medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Narges CheshmazarBiotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, 5165665813, Iran.ORCID 0000-0002-9998-8121
Maryam Hamzeh-MivehroudBiotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, 5165665813, Iran.ORCID 0000-0002-1257-0102
Salar HemmatiDrug applied research Center, Tabriz University of Medical Sciences, Tabriz, 5165665811, Iran.ORCID 0000-0002-3431-8629
Hoda AbolhasaniCellular & Molecular Research Center, Qom University of Medical Sciences, Qom, Iran.ORCID 0000-0001-9174-5304
Fatemeh HeidariCellular & Molecular Research Center, Qom University of Medical Sciences, Qom, Iran.ORCID 0000-0003-4751-8870
Hojjatollah Nozad CharoudehAnatomical Sciences Department, Faculty of Medicine, Tabriz University of Medical, Tabriz, 5166614766, Iran.ORCID 0000-0003-4883-9924
Matthes ZessinDepartment of Enzymology, Institute of Biochemistry, Martin-Luther-University Halle-Wittenberg, Halle/Saale, 06120, Germany.
Mike SchutkowskiDepartment of Enzymology, Institute of Biochemistry, Martin-Luther-University Halle-Wittenberg, Halle/Saale, 06120, Germany.ORCID 0000-0003-0919-7076
Wolfgang SipplDepartment of Medicinal Chemistry, Institute of Pharmacy, Martin-Luther-University Halle-Wittenberg, Halle/Saale, 06120, Germany.ORCID 0000-0002-5985-9261
Siavoush DastmalchiBiotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, 5165665813, Iran.ORCID 0000-0001-9427-0770
Tabriz University of Medical Sciences · IRMartin Luther University Halle-Wittenberg · DEQom University of Medical Science and Health Services · IR

Funding

Biotechnology Research Center, Tabriz University of Medical Sciences 60360Research Office and Biotechnology Research Center of Tabriz University of Medical Sciences 60360
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsBenzamidesCell ProliferationDrug DesignDrug Screening Assays, AntitumorHistone Deacetylase InhibitorsHistone DeacetylasesCell Line, TumorHumansMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipAntineoplastic AgentsbenzamideBenzamidesHistone Deacetylase InhibitorsHistone Deacetylasesbreast cancerhistone deacetylase inhibitorsmolecular dockingmolecular dynamics simulationQSARstructure modificationsynthesis

Identifiers

PMID38623995
PMCPMC11188831
OpenAlexW4394833165

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.