Evidence map›Paper›PMID 38623948›Full record

ArticleCancer control : journal of the Moffitt Cancer Center

Investigating Disparities in Hypopharyngeal/Laryngeal Cancer Survival in Florida With Geospatial Mapping Analysis.

Uche C Ezeh, Abdurrahman Al-Awady, Isabella Buitron, Ming Lee, Garrett Forman, Sophia Peifer, Alana Deo, Larissa Sweeny, Donald Weed, Erin K Kobetz and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Uche C EzehDepartment of Otolaryngology-Head and Neck Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0002-8860-6319
Abdurrahman Al-AwadyDepartment of Otolaryngology-Head and Neck Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Isabella BuitronNew York University, New York, NY, USA.ORCID 0000-0002-0897-0429
Ming LeeSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Garrett FormanDepartment of Otolaryngology-Head and Neck Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Sophia PeiferDepartment of Otolaryngology-Head and Neck Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Alana DeoUniversity of California Santa Barbara, Santa Barbara, CA, USA.
Larissa SweenyDepartment of Otolaryngology-Head and Neck Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Donald WeedDepartment of Otolaryngology-Head and Neck Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Erin K KobetzSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Isildinha M ReisDivision of Biostatistics, Department of Public Health Sciences, Sylvester Biostatistics and Bioinformatics Shared Resource, University of Miami Miller School of Medicine, Miami, FL, USA.
Elizabeth FranzmannDepartment of Otolaryngology-Head and Neck Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
University of Miami · USNew York University · USUniversity of California, Santa Barbara · US

Funding

Miami Clinical and Translational Science InstituteUM1TR004556 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Olveen Carrasquillo, ERIN N KOBETZ · 2023 to 2026
$16.0M
NCATS NIH HHS UM1 TR004556
6 · The paper itself

Abstract

objectiveIdentify predictors of overall survival (OS) after hypopharyngeal/laryngeal cancer in Florida. MATERIAL AND

methodsWe conducted a retrospective cohort study using data from the Florida Cancer Data System (FCDS) on patients diagnosed with hypopharyngeal or laryngeal cancer from 2010-2017. Primary outcome was OS. Hazard ratios (HRs) were estimated from univariable and multivariable Cox regression models for OS. Data was analyzed from November 1, 2022, to June 30, 2023.

resultsWe analyzed 6771 patients, who were primarily male (81.2%), White non-Hispanic (WNH) (78.2%), publicly insured (70.1%), married (51.8%), and residents of urban counties (73.6%). Black patients were more likely to be younger at diagnosis (38.9%), single (43.4%), to have distant SEER stage disease (25.6%). Median OS were lowest among patients who were uninsured (34 months), with hypopharyngeal site disease (18 months), and a smoking history (current: 34 months, former: 46 months, no smoking: 63 months). Multivariable Cox regression analysis showed worse OS for single/unmarried vs married (HR 1.47 [95%CI: 1.36-1.59],

conclusionOur findings suggest that sociodemographic and clinical factors impact OS from hypopharyngeal/laryngeal cancer in Florida and vary geographically within the state. These results will help guide future public health interventions.

Indexed as

Laryngeal NeoplasmsEthnicityFemaleFloridaHumansMaleProportional Hazards ModelsRetrospective Studiesepidemiologyhypopharyngeal cancerlaryngeal cancer

Identifiers

PMID38623948
PMCPMC11022680
OpenAlexW4394833296

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.