Evidence map›Paper›PMID 38623645›Full record

ArticleAmerican journal of rhinology & allergy2024

The Impact of Acute Peri-operative Particulate Matter Exposure on Endoscopic Sinus Surgery Outcomes: A Preliminary Multi-site Investigation.

Benton Tullis, Jess C Mace, Robert Hagedorn, Cassidy Nguyen, Ryan Stockard, Conner Massey, Vijay R Ramakrishnan, Daniel M Beswick, Zachary M Soler, Timothy L Smith and 2 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of rhinology & allergy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Impact of Life-Context Factors on Chronic Rhinosinusitis 22-Item Sinonasal Outcomes Test: Systematic Review + Meta-Analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Pooled it
  2. Article
  3. Establishing the PMThe Journal of allergy and clinical immunology · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Benton TullisDepartment of Otolaryngology - Head and Neck Surgery, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0003-4744-8550
Jess C MaceDivision of Rhinology and Sinus Surgery/Oregon Sinus Center, Department of Otolaryngology - Head and Neck Surgery, Oregon Health & Science University (OHSU), Portland, OR, USA.
Robert HagedornDepartment of Otolaryngology - Head and Neck Surgery, University of Utah, Salt Lake City, Utah, USA.
Cassidy NguyenDepartment of Otolaryngology - Head and Neck Surgery, University of Utah, Salt Lake City, Utah, USA.
Ryan StockardDepartment of Otolaryngology - Head and Neck Surgery, University of Utah, Salt Lake City, Utah, USA.
Conner MasseyDepartment of Otolaryngology - Head and Neck Surgery, University of Utah, Salt Lake City, Utah, USA.
Vijay R RamakrishnanDepartment of Otolaryngology - Head and Neck Surgery, University of Indiana, Indianapolis, IN, USA.
Daniel M BeswickDepartment of Otolaryngology - Head and Neck Surgery, University of California, Los Angeles, CA, USA.
Zachary M SolerDepartment of Otolaryngology -Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USA.ORCID 0000-0002-4304-595X
Timothy L SmithDivision of Rhinology and Sinus Surgery/Oregon Sinus Center, Department of Otolaryngology - Head and Neck Surgery, Oregon Health & Science University (OHSU), Portland, OR, USA.ORCID 0000-0002-6424-7083
Jeremiah A AltDepartment of Otolaryngology - Head and Neck Surgery, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0003-0560-5028
Amarbir S GillDepartment of Otolaryngology - Head and Neck Surgery, University of Michigan, Ann Arbor, MI, USA.
University of Utah · USOregon Health & Science University · USMedical University of South Carolina · USUniversity of California, Los Angeles · USUniversity of Michigan · US

Funding

DETERMINANTS OF SURGICAL OUTCOMES IN CHRONIC SINUSITISR01DC005805 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI SMITH, TIMOTHY L, SOLER, ZACHARY M · 2004 to 2020
$7.6M
NIDCD NIH HHS R01 DC005805
6 · The paper itself

Abstract

backgroundEnvironmental exposures have been postulated to play an important role in the pathophysiology of chronic rhinosinusitis (CRS). Particulate matter (PM) is one of the most widely studied ambient air pollutants, but its peri-operative impact on CRS is unknown.

objectiveTo determine the effect of acute, peri-operative PM exposure on outcomes after endoscopic sinus surgery (ESS).

methodsParticipants with CRS who self-selected ESS were prospectively enrolled. The 22-item SinoNasal Outcome Test (SNOT-22) and Medical Outcomes Study Questionnaire Short-Form 6-D (SF-6D) health utility values scores were recorded. Using residence zip codes, a secondary analysis of patient exposure to PM <2.5 μm and <10 μm (PM2.5 and PM10, respectively) was performed for the month of surgery utilizing data from Environmental Protection Agency air quality monitors. Spearman's correlation coefficients (ρ), 95% confidence intervals (CIs), and effect estimates (β) were used to determine the magnitudes of association. Simple, multivariate regression analysis was also completed.

resultsOne hundred and seven patients from four geographically unique institutions across the US were enrolled with a follow-up of 6 months. Patients with higher peri-operative PM2.5 exposure had less improvement in their SNOT-22 scores after ESS compared to those with less exposure using both univariate analysis (ρ = 0.26, 95% CI: 0.08, 0.43;

conclusionPreliminary data from this pilot study reveal that PM exposure at the time of ESS may negatively associate with post-operative improvement in sinonasal quality-of-life. Larger, population-based studies with more standardized PM exposure windows are needed to confirm the clinical significance of the present findings.

Indexed as

EndoscopyEnvironmental ExposureParanasal SinusesParticulate MatterRhinitisSinusitisAdultAgedChronic DiseaseFemaleFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesQuality of LifeParticulate Matterchronic rhinosinusitisendoscopic sinus surgeryenvironmentmulti-institutionparticulate matterperi-operative exposurepollutionquality of lifeSNOT-22surgical outcomes

Identifiers

PMID38623645
PMCPMC13058195
OpenAlexW4394853803

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.