Evidence map›Paper›PMID 38623533›Full record

ArticleJCEM case reports2024

Maternal Graves Disease Postthyroidectomy With Fetal Thyrotoxicosis and Goiter.

David Fennell, Jennifer Walsh, Barbara Cathcart, Colm P F O'Donnell, Mensud Hatunic

Open access · diamondAbstract readCase Reports
In one paragraph

Article in JCEM case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

David FennellDepartment of Endocrinology, Mater Misericordiae University Hospital, Dublin, Ireland.ORCID https://orcid.org/0000-0001-6066-8318
Jennifer WalshDepartment of Fetal Medicine, National Maternity Hospital, Dublin, Ireland.
Barbara CathcartDepartment of Fetal Medicine, National Maternity Hospital, Dublin, Ireland.
Colm P F O'DonnellDepartment of Neonatology, National Maternity Hospital, Dublin, Ireland.
Mensud HatunicDepartment of Endocrinology, Mater Misericordiae University Hospital, Dublin, Ireland.ORCID https://orcid.org/0000-0002-9693-1226
National Maternity Hospital · IEUniversity College Dublin · IEMater Misericordiae University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fetal thyrotoxicosis is a rare condition with high morbidity and mortality. It may complicate pregnancies in women with a history of Graves disease (GD) when transplacental passage of maternal TSH receptor antibodies stimulate the fetal thyroid gland and cause hyperthyroidism. We report the case of a 34-year-old woman with a history of GD and prior thyroidectomy, where fetal thyrotoxicosis at 21 weeks of gestation was suspected due to prenatal ultrasound findings of cardiac failure and fetal goiter. She was treated with high-dose carbimazole and followed closely by a multidisciplinary team. Her baby was delivered in good condition at 34 weeks' gestation and developed hyperthyroidism in the days after birth, which was successfully treated medically. This case highlights the importance of awareness of the condition among women with a history of GD, as well as the necessity for prompt diagnosis and treatment of this complex disease.

Indexed as

fetalGraveshyperthyroidismpregnancythyrotoxicosis

Identifiers

PMID38623533
PMCPMC11017107
OpenAlexW4394825266

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.