Evidence map›Paper›PMID 38623445›Full record

ArticlePlastic and reconstructive surgery. Global open2024

Impact of Gabapentin on Postoperative Hypotension in Enhanced Recovery after Surgery Protocols for Microvascular Breast Reconstruction.

Corbin E Muetterties, Jeremiah M Taylor, Diana E Kaeding, Ricardo Rosales Morales, Anissa V Nguyen, Lorna Kwan, Charles Y Tseng, Michael R Delong, Jaco H Festekjian

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Corbin E MuettertiesFrom the Division of Plastic Surgery, University of California Los Angeles, Los Angeles, Calif.
Jeremiah M TaylorFrom the Division of Plastic Surgery, University of California Los Angeles, Los Angeles, Calif.
Diana E KaedingFrom the Division of Plastic Surgery, University of California Los Angeles, Los Angeles, Calif.
Ricardo Rosales MoralesFrom the Division of Plastic Surgery, University of California Los Angeles, Los Angeles, Calif.
Anissa V NguyenFrom the Division of Plastic Surgery, University of California Los Angeles, Los Angeles, Calif.
Lorna KwanFrom the Division of Plastic Surgery, University of California Los Angeles, Los Angeles, Calif.
Charles Y TsengFrom the Division of Plastic Surgery, University of California Los Angeles, Los Angeles, Calif.
Michael R DelongFrom the Division of Plastic Surgery, University of California Los Angeles, Los Angeles, Calif.
Jaco H FestekjianFrom the Division of Plastic Surgery, University of California Los Angeles, Los Angeles, Calif.
University of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Enhanced recovery after surgery (ERAS) protocols have been associated with hypotensive episodes after autologous breast reconstruction. Gabapentin (Gaba), a nonopioid analgesic used in ERAS, has been shown to attenuate postoperative hemodynamic responses. This study assesses ERAS's impact, with and without Gaba, on postoperative hypotension after microvascular breast reconstruction. Methods: Three cohorts were studied: traditional pathway, ERAS + Gaba, and ERAS no-Gaba. We evaluated length of stay, inpatient narcotic use [morphine milligram equivalents (MME)], mean systolic blood pressure, hypotension incidence, and complications. The traditional cohort was retrospectively reviewed, whereas the ERAS groups were enrolled prospectively after the initiation of the protocol in April 2019 (inclusive of Gaba until October 2022). Results: In total, 441 patients were analyzed. The three cohorts, in the order mentioned above, were similar in age and bilateral reconstruction rates (57% versus 61% versus 60%). The ERAS cohorts, both with and without Gaba, had shorter stays ( Conclusions: Postmicrovascular breast reconstruction, ERAS + Gaba reduced overall inpatient narcotic usage, but increased hypotension incidence. Gaba removal from the ERAS protocol reduced postoperative hypotension incidence while maintaining similar stay lengths and complication rates.

Identifiers

PMID38623445
PMCPMC11018206
OpenAlexW4394823612

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.