Evidence map›Paper›PMID 38623409›Full record

ArticlePulmonary circulation2024

Factors associated with discontinuation of treatment for pulmonary arterial hypertension in the United States.

Harrison W Farber, Hayley D Germack, Nicole S Croteau, Jason C Simeone, Fei Tang, Carly J Paoli, Gurinderpal Doad, Sumeet Panjabi, Teresa De Marco

Abstract read
In one paragraph

Article in Pulmonary circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Frailty in Pulmonary Hypertension: A Multidimensional Comorbidity.Annals of the American Thoracic Society · 2025
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Harrison W FarberDivision of Pulmonary, Critical Care and Sleep Medicine Tufts Medical Center Boston Massachusetts USA.ORCID 0000-0002-0297-7902
Hayley D GermackJanssen Scientific Affairs, LLC Titusville New Jersey USA.ORCID https://orcid.org/0000-0002-0035-6301
Nicole S CroteauReal World Evidence Cytel Waltham Massachusetts USA.ORCID 0000-0001-5017-1834
Jason C SimeoneReal World Evidence Cytel Waltham Massachusetts USA.ORCID https://orcid.org/0000-0002-6141-8043
Fei TangReal World Evidence Cytel Waltham Massachusetts USA.
Carly J PaoliJanssen Scientific Affairs, LLC Titusville New Jersey USA.
Gurinderpal DoadActelion Pharmaceuticals Titusville New Jersey USA.
Sumeet PanjabiJanssen Scientific Affairs, LLC Titusville New Jersey USA.
Teresa De MarcoDivision of Cardiology University of California, San Francisco San Francisco California USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Information on factors leading to pulmonary arterial hypertension (PAH) treatment discontinuation is limited. This study analyzed 12,902 new PAH medication users to identify predictors of treatment discontinuation. Treatment by accredited pulmonary hypertension centers and combination therapy with PAH agents from different classes were less likely to result in discontinuation.

Indexed as

pulmonary arterial hypertensionrisk factorstreatment

Identifiers

PMID38623409
PMCPMC11017292

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.