Evidence map›Paper›PMID 38623381›Full record

ArticleJournal of the Endocrine Society2024

Diet in Food Insecurity: A Mediator of Metabolic Health?

Lisa L Morselli, Rabia Amjad, Roland James, Tammy L Kindel, Anne E Kwitek, Joni S Williams, Justin L Grobe, Srividya Kidambi

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Food Security and Cardio-Metabolic Risk in Individuals with Metabolic Syndrome.International journal of environmental research and public health · 2024
    Trial
  2. Article
  3. Article
  4. Diet in Food Insecurity: A Mediator of Metabolic Health?Journal of the Endocrine Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lisa L MorselliDepartment of Medicine, Division of Endocrinology and Molecular Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0003-0514-329X
Rabia AmjadCenter for Advancing Population Science, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Roland JamesDepartment of Medicine, Division of Endocrinology and Molecular Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Tammy L KindelCardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0001-7489-7189
Anne E KwitekDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0003-1024-4116
Joni S WilliamsCardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0001-8988-3556
Justin L GrobeCardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0001-9737-0873
Srividya KidambiDepartment of Medicine, Division of Endocrinology and Molecular Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID https://orcid.org/0000-0003-1589-5268
Medical College of Wisconsin · US

Funding

RAT GENOME DATABASER01HL064541 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI ANNE E. KWITEK · 1999 to 2026
$50.0M
Clinical and Translational Science AwardUL1TR001436 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI FREED, JULIE K · 2015 to 2025
$47.5M
Role of the brain Renin-Angiotensin Sys. in Cardiovas and Metabolic RegulationP01HL084207 · NHLBI · UNIVERSITY OF IOWA · PI SIGMUND, CURT DANIEL · 2007 to 2022
$30.2M
Pilot and Feasibility ProgramP30DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI RONALD N COHEN · 2013 to 2026
$20.9M
Interaction between leptin and angiotensin in the pathogenesis of obesity-hypertensionR01HL134850 · NHLBI · UNIVERSITY OF IOWA · PI Justin L Grobe · 2017 to 2026
$4.4M
Identifying Gut Microbiome Mediated Mechanisms for Diastolic Dysfunction Improvement After Bariatric SurgeryR01HL158900 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Tammy Lyn Kindel · 2022 to 2026
$2.2M
Impact of Early Life Sodium Intake on Growth and Metabolism – Role of Hypothalamic MechanismsR01DK133121 · NIDDK · MEDICAL COLLEGE OF WISCONSIN · PI GROBE, JUSTIN L, SEGAR, JEFFREY L · 2022 to 2025
$1.9M
NCATS NIH HHS UL1 TR001436NHLBI NIH HHS P01 HL084207NHLBI NIH HHS R01 HL064541NHLBI NIH HHS R01 HL134850NHLBI NIH HHS R01 HL158900NIDDK NIH HHS P30 DK020595NIDDK NIH HHS R01 DK133121
6 · The paper itself

Abstract

Objective: Food insecurity (FI) is associated with poor metabolic health. It is assumed that energy intake and diet quality underlie this association. We tested the hypothesis that dietary factors (quantity and quality) mediate the association of FI with excess weight, waist circumference and glycemic control [glycohemoglobin (A1C)]. Methods: A mediation analysis was performed on data from the National Health And Nutrition Examination Survey using FI as an independent variable; body mass index (BMI), waist circumference, and A1C as metabolic outcome variables and total energy intake, macronutrients, and diet quality measured by the Healthy Eating Index-2015 (HEI-2015) as potential mediators. Results: Despite a greater prevalence of obesity in participants experiencing FI, daily reported energy intake was similar in food-secure and -insecure subjects. In adjusted analyses of the overall cohort, none of the examined dietary factors mediated associations between FI and metabolic outcomes. In race-stratified analyses, total sugar consumption was a partial mediator of BMI in non-Hispanic Whites, while diet quality measures (HEI-2015 total score and added sugar subscore) were partial mediators of waist circumference and BMI, respectively, for those in the "other" ethnic group. Conclusion: Dietary factors are not the main factors underlying the association of FI with metabolic health. Future studies should investigate whether other social determinants of health commonly present in the context of FI play a role in this association.

Indexed as

adipositydiet qualityenergy intakefood insecuritymetabolic health

Identifiers

PMID38623381
PMCPMC11017326
OpenAlexW4393411844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.