Evidence map›Paper›PMID 38622811›Full record

ArticleJournal of biophotonics2024

U-Net enhanced real-time LED-based photoacoustic imaging.

Avijit Paul, Srivalleesha Mallidi

Open access · greenAbstract read
In one paragraph

Article in Journal of biophotonics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Avijit PaulDepartment of Biomedical Engineering, Tufts University, Medford, Massachusetts, USA.
Srivalleesha MallidiDepartment of Biomedical Engineering, Tufts University, Medford, Massachusetts, USA.ORCID 0000-0003-1547-1764
Tufts University · US

Funding

Dual function theranostic constructs for photoacoustic guided surgery and photodynamic therapyR01CA231606 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI HASAN, TAYYABA · 2019 to 2025
$3.1M
Image-guided oxygen enhanced photodynamic therapy with multi-functional nanodroplets to improve head and neck cancer treatment outcomesR01CA266701 · NCI · TUFTS UNIVERSITY MEDFORD · PI Srivalleesha Mallidi · 2022 to 2026
$1.7M
NCI NIH HHS R01 CA231606NCI NIH HHS R01 CA266701NIH HHS 5R01CA231606NIH HHS 5R01CA266701
6 · The paper itself

Abstract

Photoacoustic (PA) imaging is hybrid imaging modality with good optical contrast and spatial resolution. Portable, cost-effective, smaller footprint light emitting diodes (LEDs) are rapidly becoming important PA optical sources. However, the key challenge faced by the LED-based systems is the low light fluence that is generally compensated by high frame averaging, consequently reducing acquisition frame-rate. In this study, we present a simple deep learning U-Net framework that enhances the signal-to-noise ratio (SNR) and contrast of PA image obtained by averaging low number of frames. The SNR increased by approximately four-fold for both in-class in vitro phantoms (4.39 ± 2.55) and out-of-class in vivo models (4.27 ± 0.87). We also demonstrate the noise invariancy of the network and discuss the downsides (blurry outcome and failure to reduce the salt & pepper noise). Overall, the developed U-Net framework can provide a real-time image enhancement platform for clinically translatable low-cost and low-energy light source-based PA imaging systems.

Indexed as

Image Processing, Computer-AssistedPhantoms, ImagingPhotoacoustic TechniquesSignal-To-Noise RatioAnimalsDeep LearningLightMiceTime Factorscontrast‐to‐noise ratiofrequency spectrum analysisLED acoustic‐Xnon‐learning noise removal methodspeak signal‐to‐noise ratiophotoacousticssignal‐to‐noise ratioU‐net

Identifiers

PMID38622811
PMCPMC11164633
OpenAlexW4394850236

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.