ArticleLipids in health and disease2024
Triglyceride-glucose index predicts postoperative delirium in elderly patients with type 2 diabetes mellitus: a retrospective cohort study.
Article in Lipids in health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Diabetes mellitus is associated with an increased risk of postoperative neurocognitive disorders: a systematic review.Frontiers in medicine · 2026Pooled it
- C-reactive protein-triglyceride-glucose index predicts postoperative delirium in older surgical patients: a retrospective cohort study.Lipids in health and disease · 2026Article
- Risk factors for delirium after hip arthroplasty: An umbrella meta-analysis.International journal of nursing studies advances · 2026Review
- Association of TyG index with sepsis incidence and mortality: a prospective study with diabetes stratification.Frontiers in endocrinology · 2026Article
- Sufentanil increases delirium risk compared to fentanyl in elderly perioperative ischemic stroke patients: a retrospective cohort study.Frontiers in medicine · 2026Article
- Triglyceride-glucose index and postoperative delirium: a retrospective study exploring a lipid-related marker in neuropsychiatric risk stratification after gastric surgery.Lipids in health and disease · 2025Article
- Association between triglyceride-glucose index and postoperative delirium following cardiac surgery: a multicenter retrospective analysis.Lipids in health and disease · 2025Article
- Article
- Associations between triglyceride-glucose indices and delirium risk in critically ill patients with acute kidney injury: a retrospective study.Frontiers in endocrinology · 2025Article
- Association of triglyceride-glucose index and delirium in patients with sepsis: a retrospective study.Lipids in health and disease · 2024Article
- Correction: Triglyceride-glucose index predicts postoperative delirium in elderly patients with type 2 diabetes mellitus: a retrospective cohort study.Lipids in health and disease · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative delirium (POD) is more prevalent among elderly patients with type 2 diabetes mellitus (T2DM). Insulin resistance (IR) can be assessed using the triglyceride-glucose (TyG) index, a novel biomarker. This study aims to investigate the predictive potential of the TyG index for POD in elderly patients with T2DM. MATERIALS AND
methodsElderly patients (≥ 65) with T2DM who underwent non-neurosurgery and non-cardiac surgery were enrolled. Univariate and multivariate logistic regression analyses were conducted to assess the association between the TyG index and POD. Additionally, subgroup analyses were performed to compare the sex-specific differences in the predictive ability of the TyG index for POD.
resultsA total of 4566 patients were included in this retrospective cohort. The receiver operating characteristic (ROC) curve analysis determined the optimal cut-off value for the TyG index to be 8.678. In the univariate model, a TyG index > 8.678 exhibited an odds ratio (OR) of 1.668 (95% CI: 1.210-2.324, P = 0.002) for predicting POD. In the multivariate regression models, the ORs were 1.590 (95% CI: 1.133-2.252, P < 0.008), 1.661 (95% CI: 1.199-2.325, P < 0.003), and 1.603 (95% CI: 1.137-2.283, P = 0.008) for different models. Subgroup analyses demonstrated that the predictive ability of the TyG index was more pronounced in females compared to males.
conclusionThe TyG index shows promise as a novel biomarker for predicting the occurrence of POD in elderly surgical patients with T2DM.
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