Evidence map›Paper›PMID 38622405›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2024

Assessing Antigen-Specific T Cell Responses Through IFN-γ Enzyme-Linked Immune Absorbent Spot (ELISpot).

Julian J Freen-van Heeren, Virginia Palomares Cabeza, David Cobeta Lopez, Domenique Kivits, Irma Rensink, Annelies W Turksma, Anja Ten Brinke

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
14.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Julian J Freen-van HeerenImmunomonitoring Services, R&D, Sanquin Diagnostic Services, Amsterdam, the Netherlands. j.freenvanheeren@sanquin.nl.
Virginia Palomares CabezaDepartment of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam, the Netherlands.
David Cobeta LopezImmunomonitoring Services, R&D, Sanquin Diagnostic Services, Amsterdam, the Netherlands.
Domenique KivitsImmunomonitoring Services, R&D, Sanquin Diagnostic Services, Amsterdam, the Netherlands.
Irma RensinkImmunomonitoring Services, R&D, Sanquin Diagnostic Services, Amsterdam, the Netherlands.
Annelies W TurksmaImmunomonitoring Services, R&D, Sanquin Diagnostic Services, Amsterdam, the Netherlands. a.turksma@sanquin.nl.
Anja Ten BrinkeDepartment of Immunopathology, Sanquin Research and Landsteiner Laboratory, Amsterdam, the Netherlands. a.tenbrinke@sanquin.nl.
Sanquin · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T cells are instrumental in protecting the host against invading pathogens and the development of cancer. To do so, they produce effector molecules such as granzymes, interleukins, interferons, and perforin. For the development and immunomonitoring of therapeutic applications such as cell-based therapies and vaccines, assessing T cell effector function is paramount. This can be achieved through various methods, such as

Indexed as

Leukocytes, MononuclearT-LymphocytesAntigensEnzyme-Linked Immunosorbent AssayEnzyme-Linked Immunospot AssayGranzymesHumansAntigensGranzymesEffector functionELISpotIFN-gT cells

Identifiers

PMID38622405
OpenAlexW4394804821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.