Evidence map›Paper›PMID 38622226›Full record

ArticleSurgical endoscopy2024

Assessing the influence of parameters on tissue welding in small bowel end-to-end anastomosis in vitro and in vivo.

Caihui Zhu, Yuyan Na, Xiujun Cheng, Xiaonan Tao, Pengyao Xie, Lei Chen, Hui Zhao, Jian Qiu, Xiaodong Gu, Jianbin Xiang and 1 more

Abstract read
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In one paragraph

Article in Surgical endoscopy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Caihui ZhuSchool of Information Science and Technology, Fudan University, Shanghai, China.
Yuyan NaDepartment of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Xiujun ChengDepartment of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
Xiaonan TaoSchool of Information Science and Technology, Fudan University, Shanghai, China.
Pengyao XieSchool of Information Science and Technology, Fudan University, Shanghai, China.
Lei ChenSchool of Information Science and Technology, Fudan University, Shanghai, China.
Hui ZhaoSchool of Information Science and Technology, Fudan University, Shanghai, China.
Jian QiuSchool of Information Science and Technology, Fudan University, Shanghai, China.
Xiaodong GuDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Jianbin XiangDepartment of General Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Kefu LiuSchool of Information Science and Technology, Fudan University, Shanghai, China. kfliu@fudan.edu.cn.
Fudan University · CN

Funding

National Natural Science Foundation of China 51877046Pioneering Project of the Academy for Engineering and Technology of Fudan University gyy2018-002
6 · The paper itself

Abstract

backgroundThe use of high-frequency electric welding technology for intestinal end-to-end anastomosis holds significant promise. Past studies have focused on in vitro, and the safety and efficacy of this technology is uncertain, severely limiting the clinical application of this technology. This study investigates the impact of compression pressure, energy dosage, and duration on anastomotic quality using a homemade anastomosis device in both in vitro and in vivo settings.

methodsTwo hundred eighty intestines and 5 experimental pigs were used for in vitro and in vivo experiments, respectively. The in vitro experiments were conducted to study the effects of initial pressure (50-400 kpa), voltage (40-60 V), and time (10-20 s) on burst pressure, breaking strength, thermal damage, and histopathological microstructure of the anastomosis. Optimal parameters were then inlaid into a homemade anastomosis and used for in vivo experiments to study the postoperative porcine survival rate and the pathological structure of the tissues at the anastomosis and the characteristics of the collagen fibers.

resultsThe anastomotic strength was highest when the compression pressure was 250 kPa, the voltage was 60 V, and the time was 15 s. The degree of thermal damage to the surrounding tissues was the lowest. The experimental pigs had no adverse reactions after the operation, and the survival rate was 100%. 30 days after the operation, the surgical site healed well, and the tissues at the anastomosis changed from immediate adhesions to permanent connections.

conclusionHigh-frequency electric welding technology has a certain degree of safety and effectiveness. It has the potential to replace the stapler anastomosis in future and become the next generation of new anastomosis device.

Indexed as

Anastomosis, SurgicalIntestine, SmallPressureAnimalsIn Vitro TechniquesSwineTensile StrengthElectric weldingEnd to endIntestinal anastomosisIn vitroIn vivo

Identifiers

PMID38622226
OpenAlexW4394822463

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.