Evidence map›Paper›PMID 38622154›Full record

ArticleNature communications2024

3D printable strong and tough composite organo-hydrogels inspired by natural hierarchical composite design principles.

Quyang Liu, Xinyu Dong, Haobo Qi, Haoqi Zhang, Tian Li, Yijing Zhao, Guanjin Li, Wei Zhai

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Article
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  8. Moth-Wing-Inspired Multifunctional Metamaterials.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  9. Article
  10. Article
  11. Ultra-Robust Conductive Hydrogels Enabled by a Gradient Bond-Breaking Pseudo-Drying Strategy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  12. Review
  13. Article
  14. Review
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  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Quyang LiuDepartment of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore, Singapore.
Xinyu DongDepartment of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore, Singapore.
Haobo QiDepartment of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore, Singapore.
Haoqi ZhangDepartment of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore, Singapore.
Tian LiDepartment of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore, Singapore.
Yijing ZhaoDepartment of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore, Singapore.
Guanjin LiDepartment of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore, Singapore.
Wei ZhaiDepartment of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore, Singapore. mpezwei@nus.edu.sg.ORCID http://orcid.org/0000-0003-2307-5243

Funding

Ministry of Education - Singapore (MOE) MOE-T2EP50122-0007
6 · The paper itself

Abstract

Fabrication of composite hydrogels can effectively enhance the mechanical and functional properties of conventional hydrogels. While ceramic reinforcement is common in many hard biological tissues, ceramic-reinforced hydrogels lack a similar natural prototype for bioinspiration. This raises a key question: How can we still attain bioinspired mechanical mechanisms in composite hydrogels without mimicking a specific composition and structure? Abstracting the hierarchical composite design principles of natural materials, this study proposes a hierarchical fabrication strategy for ceramic-reinforced organo-hydrogels, featuring (1) aligned ceramic platelets through direct-ink-write printing, (2) poly(vinyl alcohol) organo-hydrogel matrix reinforced by solution substitution, and (3) silane-treated platelet-matrix interfaces. Unit filaments are further printed into a selection of bioinspired macro-architectures, leading to high stiffness, strength, and toughness (fracture energy up to 31.1 kJ/m

Identifiers

PMID38622154
PMCPMC11018840

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.