Evidence map›Paper›PMID 38621232›Full record

ReviewAnnual review of chemical and biomolecular engineering2024

Biological Upcycling of Plastics Waste.

Ross R Klauer, D Alex Hansen, Derek Wu, Lummy Maria Oliveira Monteiro, Kevin V Solomon, Mark A Blenner

Abstract readReview
In one paragraph

Review in Annual review of chemical and biomolecular engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Hydrophobins fromEnvironmental science & technology · 2025
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ross R KlauerDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA; email: kvs@udel.edu, blenner@udel.edu.
D Alex HansenDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA; email: kvs@udel.edu, blenner@udel.edu.
Derek WuDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA; email: kvs@udel.edu, blenner@udel.edu.
Lummy Maria Oliveira MonteiroDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA; email: kvs@udel.edu, blenner@udel.edu.
Kevin V SolomonDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA; email: kvs@udel.edu, blenner@udel.edu.
Mark A BlennerDepartment of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA; email: kvs@udel.edu, blenner@udel.edu.

Funding

Chemistry-Biology Interface Predoctoral Training Grant 2024-2029T32GM133395 · NIGMS · UNIVERSITY OF DELAWARE · PI Catherine Leimkuhler Grimes · 2019 to 2026
$3.7M
NIGMS NIH HHS T32 GM133395
6 · The paper itself

Abstract

Plastic wastes accumulate in the environment, impacting wildlife and human health and representing a significant pool of inexpensive waste carbon that could form feedstock for the sustainable production of commodity chemicals, monomers, and specialty chemicals. Current mechanical recycling technologies are not economically attractive due to the lower-quality plastics that are produced in each iteration. Thus, the development of a plastics economy requires a solution that can deconstruct plastics and generate value from the deconstruction products. Biological systems can provide such value by allowing for the processing of mixed plastics waste streams via enzymatic specificity and using engineered metabolic pathways to produce upcycling targets. We focus on the use of biological systems for waste plastics deconstruction and upcycling. We highlight documented and predicted mechanisms through which plastics are biologically deconstructed and assimilated and provide examples of upcycled products from biological systems. Additionally, we detail current challenges in the field, including the discovery and development of microorganisms and enzymes for deconstructing non-polyethylene terephthalate plastics, the selection of appropriate target molecules to incentivize development of a plastic bioeconomy, and the selection of microbial chassis for the valorization of deconstruction products.

Indexed as

Biodegradation, EnvironmentalPlasticsRecyclingBacteriaHumansWaste ProductsPlasticsWaste Productsbiological plastic deconstructionbiological plastic upcyclingenzyme discoveryplastics bioeconomy

Identifiers

PMID38621232
PMCPMC11575423

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.