ArticleProceedings of the National Academy of Sciences of the United States of America1985
Visualization of the protein associations in the erythrocyte membrane skeleton.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1985. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers.
What it found
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Who cites it
144 citing papers in PubMed, 398 citations in OpenAlex.
- A correlation-based tool for quantifying membrane periodic skeleton associated periodicity.Frontiers in neuroinformatics · 2025Article
- Piezo1 Regulation Involves Lipid Domains and the Cytoskeleton and Is Favored by the Stomatocyte-Discocyte-Echinocyte Transformation.Biomolecules · 2023Article
- Effective cell membrane tension protects red blood cells against malaria invasion.PLoS computational biology · 2023Article
- Spectrins: molecular organizers and targets of neurological disorders.Nature reviews. Neuroscience · 2023Review
- β-heavy-spectrin stabilizes the constricting contractile ring during cytokinesis.The Journal of cell biology · 2023Article
- Reticulocyte Maturation.Membranes · 2022Review
- Investigation of Red Blood Cells by Atomic Force Microscopy.Sensors (Basel, Switzerland) · 2022Article
- Nanoscale dynamics of actin filaments in the red blood cell membrane skeleton.Molecular biology of the cell · 2022Article
- Multimodal imaging reveals membrane skeleton reorganisation during reticulocyte maturation and differences in dimple and rim regions of mature erythrocytes.Journal of structural biology: X · 2022Article
- Plastin and spectrin cooperate to stabilize the actomyosin cortex during cytokinesis.Current biology : CB · 2021Article
- Nucleic Acid Delivery with Red-Blood-Cell-Based Carriers.International journal of molecular sciences · 2021Review
- Quantifying the influences of radiation therapy on deformability of human red blood cells by dual-beam optical tweezers.RSC advances · 2021Article
- Constitutive Model of Erythrocyte Membranes with Distributions of Spectrin Orientations and Lengths.Biophysical journal · 2020Article
- Complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponse.Nature communications · 2020Article
- A Fresh Look at the Structure, Regulation, and Functions of Fodrin.Molecular and cellular biology · 2020Review
- Coarse-Grained Modeling of Pore Dynamics on the Red Blood Cell Membrane under Large Deformations.Biophysical journal · 2020Article
- A Na,K-ATPase-Fodrin-Actin Membrane Cytoskeleton Complex is Required for Endothelial Fenestra Biogenesis.Cells · 2020Article
- Cargo hold and delivery: Ankyrins, spectrins, and their functional patterning of neurons.Cytoskeleton (Hoboken, N.J.) · 2020Review
- The Spectrinome: The Interactome of a Scaffold Protein Creating Nuclear and Cytoplasmic Connectivity and Function.Experimental biology and medicine (Maywood, N.J.) · 2019Review
- βII-spectrin promotes mouse brain connectivity through stabilizing axonal plasma membranes and enabling axonal organelle transport.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
84 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
We have obtained clear images of the erythrocyte membrane skeleton from negatively stained preparations that originate directly from the intact cell but in which the spectrin meshwork is artificially spread to allow close inspection. Our procedure requires less than 2 min at 5 degrees C in phosphate buffers. We find 200-nm-long spectrin tetramers crosslinked by junctional complexes. Each junction contains a regular 37-nm rod, probably an actin oligomer of approximately 13 monomers. Densities appear at variable places in the meshwork but distinct globules occur with great frequency 78 nm from the spectrin tetramer's junctional insertion end, very close to the known binding site for ankyrin. Most frequently, five or six spectrin tetramers insert into each junction, producing a meshwork that displays remarkably regular long range order.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.