Evidence map›Paper›PMID 38621207›Full record

ArticleZebrafish2024

Lectins As Effective Tools in the Study of the Biliary Network and the Parenchymal Architecture of the Zebrafish (

Hayden Bhavsar, Zoe Robinson, Matthew Benson, Feven Getachew, Juan Manuel González-Rosa, Pascal J Lafontant

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zebrafish, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hayden BhavsarBiology Department, Grinnell College, Grinnell, Iowa, USA.
Zoe RobinsonBiology Department, Grinnell College, Grinnell, Iowa, USA.
Matthew BensonBiology Department, Grinnell College, Grinnell, Iowa, USA.
Feven GetachewBiology Department, Grinnell College, Grinnell, Iowa, USA.
Juan Manuel González-RosaCardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Pascal J LafontantBiology Department, Grinnell College, Grinnell, Iowa, USA.ORCID 0000-0001-7230-6883
Grinnell College · USMassachusetts General Hospital · US

Funding

Identifying new regulators of cardiac fibrosis and inflammation using zebrafishR01HL164749 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Juan Manuel Gonzalez-Rosa · 2022 to 2026
$2.0M
NHLBI NIH HHS R01 HL164749
6 · The paper itself

Abstract

Lectins are carbohydrate-binding proteins with specific affinity to glycoconjugates expressed in various tissues. Lectins are of substantial utility as research, histochemical, and diagnostic tools in mammalian systems. Reactivity of 12 commonly used plant-based lectins was studied in zebrafish liver. Four lectins, tomato lectin (TL), wheat germ agglutinin, concanavalin A, and Jacalin showed strong reactivity to hepatic parenchymal structures. Importantly, TL reacted to glycoconjugates within segments of the larval and adult intrahepatic biliary network, from canaliculi to bile ducts. We provide evidence that lectins can serve as important histochemical tools to investigate the structural and functional characteristics of the zebrafish liver.

Indexed as

LectinsZebrafishAnimalsGlycoconjugatesHistocytochemistryLiverMammalsGlycoconjugatesLectinsbilecanaliculihepatocyteslectinliverzebrafish

Identifiers

PMID38621207
PMCPMC11035847
OpenAlexW4394853815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.