Evidence map›Paper›PMID 38621193›Full record

ArticleJCO clinical cancer informatics2024

Organizational Breast Cancer Data Mart: A Solution for Assessing Outcomes of Imaging and Treatment.

Margarita L Zuley, Jonathan Silverstein, Durwin Logue, Richard S Morgan, Rohit Bhargava, Priscilla F McAuliffe, Adam M Brufsky, Andriy I Bandos, Robert M Nishikawa

Abstract read
In one paragraph

Article in JCO clinical cancer informatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Breast Cancer Screening Interval: Effect on Rate of Late-Stage Disease at Diagnosis and Overall Survival.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Margarita L ZuleyUniversity of Pittsburgh, School of Medicine & University of Pittsburgh Medical Center, Department of Radiology, Division of Breast Imaging, Pittsburgh, PA.ORCID 0000-0003-2127-8346
Jonathan SilversteinUniversity of Pittsburgh, School of Medicine, Department of Biomedical Informatics, Pittsburgh, PA.ORCID 0000-0002-9252-6039
Durwin LogueUniversity of Pittsburgh, School of Medicine, Department of Radiology, Imaging Research, Pittsburgh, PA.
Richard S MorganUniversity of Pittsburgh, School of Medicine, Department of Biomedical Informatics, Pittsburgh, PA.
Rohit BhargavaUniversity of Pittsburgh, School of Medicine, Department of Pathology and Pathology at Magee-Womens Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA.ORCID 0000-0002-1225-8418
Priscilla F McAuliffeUniversity of Pittsburgh, School of Medicine, Department of Surgery and Breast Surgical Oncology at Magee-Womens Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA.
Adam M BrufskyUniversity of Pittsburgh, School of Medicine & University of Pittsburgh Medical Center, Division of Hematology/Oncology, Pittsburgh, PA.ORCID 0000-0001-8080-7960
Andriy I BandosUniversity of Pittsburgh, Graduate School of Public Health, Biostatistics, Pittsburgh, PA.ORCID 0000-0001-5629-1415
Robert M NishikawaUniversity of Pittsburgh, School of Medicine, Department of Radiology, Imaging Research, Pittsburgh, PA.ORCID 0000-0001-7720-9951

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOHN C. BYRD · 1988 to 2026
$158.0M
NCI NIH HHS P30 CA047904
6 · The paper itself

Abstract

purposeIn the United States, a comprehensive national breast cancer registry (CR) does not exist. Thus, care and coverage decisions are based on data from population subsets, other countries, or models. We report a prototype real-world research data mart to assess mortality, morbidity, and costs for breast cancer diagnosis and treatment.

methodsWith institutional review board approval and Health Insurance Portability and Accountability Act (HIPPA) compliance, a multidisciplinary clinical and research data warehouse (RDW) expert group curated demographic, risk, imaging, pathology, treatment, and outcome data from the electronic health records (EHR), radiology (RIS), and CR for patients having breast imaging and/or a diagnosis of breast cancer in our institution from January 1, 2004, to December 31, 2020. Domains were defined by prebuilt views to extract data denormalized according to requirements from the existing RDW using an export, transform, load pattern. Data dictionaries were included. Structured query language was used for data cleaning.

resultsFive-hundred eighty-nine elements (EHR 311, RIS 211, and CR 67) were mapped to 27 domains; all, except one containing CR elements, had cancer and noncancer cohort views, resulting in a total of 53 views (average 12 elements/view; range, 4-67). EHR and RIS queries returned 497,218 patients with 2,967,364 imaging examinations and associated visit details. Cancer biology, treatment, and outcome details for 15,619 breast cancer cases were imported from the CR of our primary breast care facility for this prototype mart.

conclusionInstitutional real-world data marts enable comprehensive understanding of care outcomes within an organization. As clinical data sources become increasingly structured, such marts may be an important source for future interinstitution analysis and potentially an opportunity to create robust real-world results that could be used to support evidence-based national policy and care decisions for breast cancer.

Indexed as

Breast NeoplasmsData WarehousingDiagnostic ImagingElectronic Health RecordsFemaleHumansRegistriesUnited States

Identifiers

PMID38621193
PMCPMC11161224

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.