Evidence map›Paper›PMID 38621006›Full record

ArticleTrends in anaesthesia & critical care2023

A novel negative pressure isolation device reduces aerosol exposure: A randomized controlled trial.

John S Shin, Muchuan Niu, Haoxuan Chen, Tristan Grogan, Jason S Lee, Elaine C Liew, Soban Umar, Dong Ho Shin, Yifang Zhu, Nir N Hoftman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Trends in anaesthesia & critical care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

John S ShinDepartment of Anesthesiology and Perioperative Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Muchuan NiuDepartment of Environmental Health Sciences, Fielding School of Public Health, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Haoxuan ChenDepartment of Environmental Health Sciences, Fielding School of Public Health, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Tristan GroganDepartment of Environmental Health Sciences, Fielding School of Public Health, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Jason S LeeDepartment of Anesthesiology and Perioperative Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Elaine C LiewDepartment of Anesthesiology and Perioperative Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Soban UmarDepartment of Anesthesiology and Perioperative Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Dong Ho ShinDepartment of Anesthesiology and Perioperative Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Yifang ZhuDepartment of Environmental Health Sciences, Fielding School of Public Health, University of California Los Angeles (UCLA), Los Angeles, CA, USA.
Nir N HoftmanDepartment of Anesthesiology and Perioperative Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: The COVID-19 pandemic has led to a proliferation of intubation barriers designed to protect healthcare workers from infection. We developed the Suction-Assisted Local Aerosol Containment Chamber (SLACC) and tested it in the operating room. The primary objectives were to determine the ease and safety of airway management with SLACC, and to measure its efficacy of aerosol containment to determine if it significantly reduces exposure to health care workers. Methods: In this randomized clinical trial, adult patients scheduled to undergo elective surgery with general endotracheal anesthesia were screened and informed consent obtained from those willing to participate. Patients were randomized to airway management either with or without the SLACC device. Patients inhaled nebulized saline before and during anesthesia induction to simulate the size and concentration of particles seen with severe symptomatic SARS-CoV-2 infection. Results: 79 patients were enrolled and randomized. Particle number concentration (PNC) at the patients' and healthcare workers' locations were measured and compared between the SLACC vs. control groups during airway management. Ease and success of tracheal intubation were recorded for each patient. All intubations were successful and time to intubation was similar between the two groups. Healthcare workers were exposed to significantly lower particle number concentrations (#/cm3) during airway management when SLACC was utilized vs. control. The particle count outside SLACC was reduced by 97% compared to that inside the device. Conclusions: The SLACC device does not interfere with airway management and significantly reduces healthcare worker exposure to aerosolized particles during airway management.

Indexed as

AerosolCOVID-19Healthcare workerIsolation deviceRandomized clinical trial

Identifiers

PMID38621006
PMCPMC9986117

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.