ArticleTrends in anaesthesia & critical care2022
Effect of head-end of bed elevation on respiratory mechanics in mechanically ventilated patients with moderate-to-severe COVID-19 ARDS - A cohort study.
Article in Trends in anaesthesia & critical care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
- Characteristics and outcomes of pulmonary barotrauma in patients with COVID-19 ARDS: A retrospective observational study.Qatar medical journal · 2024Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Head-end elevation (HEE) is known to improve oxygenation and respiratory mechanics. In ARDS, poor lung compliance limits positive pressure ventilation causing delivery of inadequate minute ventilation (MVe). We observed that, in moderate-to-severe COVID-19 ARDS, the respiratory system compliance (Crs) reduces upon elevating the head-end of the bed, and vice-versa, which can be utilized to improve ventilation and avoid respiratory acidosis.We hypothesized that increasing the degree of HEE reduces Crs. Methods: We included 20 consecutive mechanically ventilated, moderate-to-severe COVID-19 ARDS patients in this pilot study (CTRI/2021/06/034,182). The Crs, Mve and Rinsp were recorded at 0°, 10°, 20° and 30° HEE. Repeated measures ANOVA was used to determine significant differences in measurements with increasing degrees and repeated measures correlation ( Results: Repeated measures ANOVA showed a significant difference (p < 0.0001) between values of Crs, MVe and Rinsp. Conclusions: Increasing degree of HEE reduces compliance in moderate-to-severe COVID-19 ARDS. Reducing HEE may optimize ventilation and mitigate ventilator induced lung injury.
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Registered trials
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