Evidence map›Paper›PMID 38620955›Full record

ArticleClinical complementary medicine and pharmacology2021

Treatment Effects of Integrated TCM and Western Medicine Treatment Scheme on COVID-19: A Single-armed Clinical Trial.

Jianfeng Bao, Zhijun Xie, Shourong Liu, Lin Huang, Jing Sun, Yujun Tang, Haiping Chen, Jianjiang Qi, Jianchun Guo, Liangbin Miao and 12 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical complementary medicine and pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 2 institutions in 1 country.

Jianfeng BaoZhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.
Zhijun XieZhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.
Shourong LiuZhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.
Lin HuangZhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.
Jing SunThe Second Hospital affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310005, China.
Yujun TangZhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.
Haiping ChenHangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310014, China.
Jianjiang QiHangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310014, China.
Jianchun GuoHangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310014, China.
Liangbin MiaoHangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310014, China.
Zhaoyi LiHangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310014, China.
Hui YangZhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.
Yi ZhangZhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.
Zhiyu LiZhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.
Yuan XuHangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310014, China.
Shengyou LinGuangxing Hospital affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310007, China.
Yunhao XunHangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310014, China.
Li ZhangGuangxing Hospital affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310007, China.
Jie BaoZhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.
Zhaobin CaiZhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.
Jinsong HuangHangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310014, China.
Chengping WenZhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.
Zhejiang Chinese Medical University · CNHangzhou Xixi hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Backgroud: The outbreak of COVID-19 has brought unprecedented perils to human health and raised public health concerns in more than two hundred countries. Safe and effective treatment scheme is needed urgently. Objective: To evaluate the effects of integratedTCM and western medicine treatment scheme on COVID-19. Methods: A single-armed clinical trial was carried out in Hangzhou Xixi Hospital, an affiliated hospital with Zhejiang Chinese Medical University. 102 confirmed cases were screened out from 725 suspected cases and 93 of them were treated with integrated TCM and western medicine treatment scheme. Results: 83 cases were cured, 5 cases deteriorated, and 5 cases withdrew from the study. No deaths were reported. The mean relief time of fever, cough, diarrhea, and fatigue were (4.78 ± 4.61) days, (7.22 ± 4.99) days, (5.28 ± 3.39) days, and (5.28 ± 3.39) days, respectively. It took (14.84 ± 5.50) days for SARS-CoV-2 by nucleic acid amplification-based testing to turn negative. Multivariable cox regression analysis revealed that age, BMI, PISCT, BPC, AST, CK, BS, and UPRO were independent risk factors for COVID-19 treatment. Conclusion: Our study suggested that integrated TCM and western medicine treatment scheme was effective for COVID-19.

Indexed as

Chinese medicineClinical trialCOVID-19Novel coronavirus pneumonia

Identifiers

PMID38620955
PMCPMC8590636
OpenAlexW3211835148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.