Evidence map›Paper›PMID 38620766›Full record

ArticleClinical immunology communications2022

Meningoradiculitis post-COVID-19 mRNA vaccination: A case report.

Alexandre Landry, Stéphanie Crapoulet, Luc H Boudreau, Christine Bourque, Lyle Weston, Nicholas Pilote, Guillaume Desnoyers, Ludivine Chamard-Witkowski

Erratum issuedOpen access · goldAbstract readCase Reports
In one paragraph

Article in Clinical immunology communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Considerations on COVID-19 vaccination.Clinical immunology communications · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Alexandre LandryCentre de formation médicale du Nouveau-Brunswick, Pavillon J.-Raymond-Frenette, 50 de la Francophonie St., Moncton, NB E1A 7R1, Canada.
Stéphanie CrapouletRegional Office of Research Services, Dr.-Georges-L.-Dumont University Hospital Center, Vitalité Health Network, 330 Université Ave., Moncton, NB E1C 2Z3, Canada.
Luc H BoudreauDepartment of Chemistry and Biochemistry, Pavillon Léopold-Taillon, University of Moncton, 18 Antonine-Maillet Ave., Moncton, NB E1A 3E9, Canada.
Christine BourqueDepartment of Infectious Disease, Dr-Georges-L.-Dumont University Hospital Center, Vitalité Health Network, 330 Université Ave., Moncton, NB E1C 2Z3, Canada.
Lyle WestonDepartment of Neurology, The Moncton Hospital, Horizon Health network, 135 MacBeath Ave., Moncton, NB E1C 6Z8, Canada.
Nicholas PiloteDepartment of Radiology, Dr-Georges-L.-Dumont University Hospital Center, Vitalité Health Network, 330 Université Ave., Moncton, NB E1C 2Z3, Canada.
Guillaume DesnoyersNB Diagnostic Virology Reference Center, Dr-Georges-L.-Dumont University Hospital Center, Vitalité Health Network, 330 Université Ave., Moncton, NB E1C 2Z3, Canada.
Ludivine Chamard-WitkowskiCentre de formation médicale du Nouveau-Brunswick, Pavillon J.-Raymond-Frenette, 50 de la Francophonie St., Moncton, NB E1A 7R1, Canada.
Dr. Georges-L.-Dumont University Hospital Centre · CAMoncton Hospital · CAUniversité de Moncton · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a rare case of meningoradiculitis occurring after mRNA COVID-19 vaccination. This patient, with a history of inflammatory arthritis following rubella vaccination, presented to the emergency department 4 days after her vaccination with both central and radicular nervous system symptoms. Symptoms included pain, sensory and motor deficits in L5 roots distribution, along with signs of central irritation, such as headache, difficulty concentrating and a Babinski sign. MRI showed bilateral L5 nerve roots enhancement. Lumbar puncture showed elevated protein and IgG, and relevant serologies excluded common causes. Prednisone and physical therapy helped the patient to achieve near complete recovery nine weeks after presentation. We concluded that this patient presented meningoradiculitis probably secondary to her vaccination in a context of possible overactive immune system. While such presentations might be rare, and do not constitute a general reason to abstain from vaccination, they must be well recognized and treated.

Indexed as

Case reportCovid-19 vaccineMeningoradiculitismRNA vaccinePost-vaccine reactionRadiculitis

Identifiers

PMID38620766
PMCPMC8923012
OpenAlexW4220846499

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.