Evidence map›Paper›PMID 38620665›Full record

ArticleThrombosis update2020

Venous thrombotic events in severe and critically COVID-19 patients despite high dose prophylactic low-molecular-weight heparin.

Chantal Visser, Reinier A Sprenger, Hans J van den Bout, Dirk P Boer, Rachida El Moussaoui, Jan G den Hollander

Erratum issuedOpen access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Thrombosis update, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chantal VisserDepartment of Internal Medicine, Maasstad Hospital, Locatiecode 1L3024, Postbus 9100, 3007 AC, Rotterdam, the Netherlands.
Reinier A SprengerDepartment of Internal Medicine, Maasstad Hospital, Locatiecode 1L3024, Postbus 9100, 3007 AC, Rotterdam, the Netherlands.
Hans J van den BoutDepartment of Intensive Care, Maasstad Hospital, Locatiecode 1L3024, Postbus 9100, 3007 AC, Rotterdam, the Netherlands.
Dirk P BoerDepartment of Intensive Care, Maasstad Hospital, Locatiecode 1L3024, Postbus 9100, 3007 AC, Rotterdam, the Netherlands.
Rachida El MoussaouiDepartment of Internal Medicine, Maasstad Hospital, Locatiecode 1L3024, Postbus 9100, 3007 AC, Rotterdam, the Netherlands.
Jan G den HollanderDepartment of Internal Medicine, Maasstad Hospital, Locatiecode 1L3024, Postbus 9100, 3007 AC, Rotterdam, the Netherlands.
Maasstad Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypercoagulation is one of the most distinct prognostic factors of patients with COVID-19 and has been associated with arterial thrombosis and other venous thrombotic events (VTE). Bleeding complications are far less encountered. The International Society on Thrombosis and Haemostasis (ISTH) guidance advises giving prophylactic low-molecular-weight heparin (LMWH) to prevent these events, although there is evidence that the incidence remains high despite using prophylactic LMWH. We describe three cases of COVID-19 pneumonia that were admitted to our intensive care unit (ICU) and developed acute pulmonary embolisms (APE) despite high dosage prophylactic LMWH. These cases raise concerns about using prophylactic LMWH instead of therapeutic anticoagulation in severe and critically COVID-19 patients.

Indexed as

AnticoagulantsBlood CoagulationCOVID-19HeparinLow-molecular-weightPulmonary embolism

Identifiers

PMID38620665
PMCPMC7434635
OpenAlexW3049500974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.