Evidence map›Paper›PMID 38620328›Full record

ArticleEngineered regeneration2020

Applications of PLA in modern medicine.

Vincent DeStefano, Salaar Khan, Alonzo Tabada

Registry-linked trialAbstract read
In one paragraph

Article in Engineered regeneration, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07774052 (Computer Guided Immediate Implant Placement in Mandibular Molars Using Patient Specific 3D Printed Polylactic Acid Graft Versus Conventional Immediate Implant Placement With Xenograft), which is not on this map. Cited by 174 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
174citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07774052 nacompletednot on this mapstarted 2024, after this paper: background citation

Computer Guided Immediate Implant Placement in Mandibular Molars Using Patient Specific 3D Printed Polylactic Acid Graft Versus Conventional Immediate Implant Placement With Xenograft

TypeinterventionalSponsorMahmoud Fawzy Mahmoud MohamedRan2024 to 2026Enrolled17ConditionsImmediate Implant Placement in Mandibular Molar Extraction SocketsArmsPatient-Specific 3D-Printed PLA Socket Guide and Root-Form Scaffold, Conventional Immediate Implant Placement
3 · Its place in the literature

Who cites it

174 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Tracheal Tissue Engineering: Advances and Challenges.Bioengineering (Basel, Switzerland) · 2026
    Review
  6. A Composite Based onPolymers · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Development of a Platform forAerosol science and technology : the journal of the American Association for Aerosol Research · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

114 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vincent DeStefanoDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794, USA.
Salaar KhanDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794, USA.
Alonzo TabadaDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polylactic acid (PLA) is a versatile biopolymer. PLA is synthesized with ease from abundant renewable resources and is biodegradable. PLA has shown promise as a biomaterial in a plethora of healthcare applications such as tissue engineering or regenerative medicine, cardiovascular implants, dental niches, drug carriers, orthopedic interventions, cancer therapy, skin and tendon healing, and lastly medical tools / equipment. PLA has demonstrated instrumental importance as a three-dimensionally (3D) printable biopolymer, which has further been bolstered by its role during the Coronavirus Disease of 2019 (Covid-19) global pandemic. As an abundant filament, PLA has created desperately needed personal protective equipment (PPE) and ventilator modifications. As polymer chemistry continues to advance, so too will the applications and continued efficacy of PLA-based modalities.

Indexed as

Cancer therapyCardiovascularDentalDrug carriersOrthopedicsPolylactic acidPolymersskin/tendon healingsurgical toolsTissue engineering

Identifiers

PMID38620328
PMCPMC7474829

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.