Evidence map›Paper›PMID 38620081›Full record

ArticleCirculation2024

Nanopore Detection of METTL3-Dependent m6A-Modified mRNA Reveals a New Mechanism Regulating Cardiomyocyte Mitochondrial Metabolism.

Charles P Rabolli, Isabel S Naarmann-de Vries, Catherine A Makarewich, Kedryn K Baskin, Christoph Dieterich, Federica Accornero

Open access · greenAbstract readLetter
In one paragraph

Article in Circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. The Role of NMedComm · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. The mRNA (New York, N.Y.) · 2025
    Article
  6. Article
  7. Review
  8. Regulatory mechanisms of mAmerican journal of translational research · 2025
    Review
  9. YTHDF1 is pivotal for maintenance of cardiac homeostasis.Journal of molecular and cellular cardiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Charles P RabolliDepartments of Physiology and Cell Biology (C.P.R., K.K.B., F.A.), The Ohio State University, Columbus.ORCID 0000-0002-4383-8706
Isabel S Naarmann-de VriesSection of Bioinformatics and Systems Cardiology, Klaus Tschira Institute for Integrative Computational Cardiology (I.S.N.-d.V., C.D.), University Hospital Heidelberg, Germany.
Catherine A MakarewichThe Heart Institute, Division of Molecular Cardiovascular Biology, Cincinnati Children's Hospital Medical Center, OH (C.A.M.).ORCID 0000-0001-6907-4401
Kedryn K BaskinDepartments of Physiology and Cell Biology (C.P.R., K.K.B., F.A.), The Ohio State University, Columbus.ORCID 0000-0003-3187-9655
Christoph DieterichSection of Bioinformatics and Systems Cardiology, Klaus Tschira Institute for Integrative Computational Cardiology (I.S.N.-d.V., C.D.), University Hospital Heidelberg, Germany.
Federica AccorneroDepartments of Physiology and Cell Biology (C.P.R., K.K.B., F.A.), The Ohio State University, Columbus.ORCID 0000-0003-1209-7228
Brown University · USHeidelberg University · DECincinnati Children's Hospital Medical Center · USThe Ohio State University Wexner Medical Center · US

Funding

Post-transcriptional regulation of cardiac hypertrophyR01HL136951 · NHLBI · OHIO STATE UNIVERSITY · PI Federica Accornero · 2017 to 2026
$4.7M
Transcriptional Coordination and Gene Regulation by MED12 in the CardiomyocyteR01HL166520 · NHLBI · OHIO STATE UNIVERSITY · PI KEDRYN K BASKIN · 2023 to 2026
$2.3M
Mechanistic characterization of a new master regulator of cardiac virus infectionsR01HL154001 · NHLBI · OHIO STATE UNIVERSITY · PI ACCORNERO, FEDERICA, YOUNT, JACOB · 2020 to 2023
$2.3M
METTL3 in regulation of the aging processR01AG079842 · NIA · OHIO STATE UNIVERSITY · PI Federica Accornero · 2023 to 2026
$2.1M
Microprotein Regulation of Mitochondrial FunctionR01HL160569 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI Catherine A Makarewich · 2022 to 2026
$2.0M
YTHDF3 as a critical regulator of cardiac functionF30HL165812 · NHLBI · OHIO STATE UNIVERSITY · PI RABOLLI, CHARLES P. · 2023 to 2025
$142k
NHLBI NIH HHS F30 HL165812NHLBI NIH HHS R01 HL136951NHLBI NIH HHS R01 HL154001NHLBI NIH HHS R01 HL160569NHLBI NIH HHS R01 HL166520NIA NIH HHS R01 AG079842
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdenineMyocytes, CardiacNanoporesHumansMethyltransferasesRNA, Messenger6-methyladenineAdenineMethyltransferasesMETTL3 protein, humanRNA, Messengermitochondriamyocytes, cardiacnanoporesRNA, messenger

Identifiers

PMID38620081
PMCPMC11882014
OpenAlexW4394805727

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.