Evidence map›Paper›PMID 38619971›Full record

ArticleCell cycle (Georgetown, Tex.)2024

Repression of YEATS2 induces cellular senescence in hepatocellular carcinoma and inhibits tumor growth.

Qi Wu, Quan Zheng, Lei Yuan, Dandan Gao, Yabing Hu, Xinqing Jiang, Qiaocheng Zhai, Ming Liu, Lifeng Xu, Heng Xu and 2 more

Open access · greenAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Qi WuDepartment of Hepatobiliary Surgery, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, China.
Quan ZhengDepartment of Hepatobiliary Surgery, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, China.
Lei YuanDepartment of Hepatobiliary Surgery, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, China.
Dandan GaoSchool of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Yabing HuSchool of Basic Medical Sciences, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Xinqing JiangThe Joint Innovation Center for Engineering in Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Qiaocheng ZhaiThe Joint Innovation Center for Engineering in Medicine, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, China.
Ming LiuThe Joint Innovation Center for Engineering in Medicine, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, China.
Lifeng XuThe Joint Innovation Center for Engineering in Medicine, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, China.
Heng XuDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.
Jinlin YeThe Joint Innovation Center for Engineering in Medicine, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, China.
Feng ZhangThe Joint Innovation Center for Engineering in Medicine, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, China.ORCID 0000-0002-6751-0377
Wenzhou Medical University · CNSichuan University · CNXuzhou Medical College · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) stands as the third leading cause of cancer-related fatalities globally. In this study, we observed a significant increase in the expression level of the

Indexed as

Carcinoma, HepatocellularCell ProliferationCellular SenescenceLiver NeoplasmsAnimalsCell Line, TumorCyclin-Dependent Kinase Inhibitor p21DNA DamageGene Expression Regulation, NeoplasticHumansMaleMiceMice, Inbred BALB CMice, NudeMicroRNAsProto-Oncogene Proteins c-mycCyclin-Dependent Kinase Inhibitor p21MicroRNAsProto-Oncogene Proteins c-mycTumor Suppressor Protein p53hepatocellular carcinomasenescenceYEATS2

Identifiers

PMID38619971
PMCPMC11174065
OpenAlexW4394806022

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.