Evidence map›Paper›PMID 38619783›Full record

ArticleThe ultrasound journal2024

Impaired cerebral autoregulation detected in early prevasospasm period is associated with unfavorable outcome after spontaneous subarachnoid hemorrhage: an observational prospective pilot study.

Edvinas Chaleckas, Vilma Putnynaite, Indre Lapinskiene, Aidanas Preiksaitis, Mindaugas Serpytis, Saulius Rocka, Laimonas Bartusis, Vytautas Petkus, Arminas Ragauskas

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The ultrasound journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06028906 (Research and Development of Innovative Method and Technology for Cerebral Perfusion Pressure Diagnosis), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06028906 unknown statusnot on this map

Research and Development of Innovative Method and Technology for Cerebral Perfusion Pressure Diagnosis

TypeobservationalSponsorVilnius UniversityRan2021 to 2024Enrolled80ConditionsTrauma, Brain, Hemorrhage CerebralArmsMultimodal physiological monitoring and cerebral autoregulation monitoring
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Edvinas ChaleckasHealth Telematics Science Institute, Kaunas University of Technology, K. Barsausko str. 59, Kaunas, LT-51423, Lithuania.
Vilma PutnynaiteHealth Telematics Science Institute, Kaunas University of Technology, K. Barsausko str. 59, Kaunas, LT-51423, Lithuania.
Indre LapinskieneClinic of Anesthesiology and Intensive Care, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Aidanas PreiksaitisClinic of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Mindaugas SerpytisClinic of Anesthesiology and Intensive Care, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Saulius RockaClinic of Neurology and Neurosurgery, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Laimonas BartusisHealth Telematics Science Institute, Kaunas University of Technology, K. Barsausko str. 59, Kaunas, LT-51423, Lithuania.
Vytautas PetkusHealth Telematics Science Institute, Kaunas University of Technology, K. Barsausko str. 59, Kaunas, LT-51423, Lithuania. vytautas.petkus@ktu.lt.ORCID http://orcid.org/0000-0002-8964-0738
Arminas RagauskasHealth Telematics Science Institute, Kaunas University of Technology, K. Barsausko str. 59, Kaunas, LT-51423, Lithuania.
Kaunas University of Technology · LTVilnius University · LT

Funding

Lietuvos Mokslo Taryba 01.2.2-LMT-K-718-03-0091Lietuvos Mokslo Taryba MIP-20-216
6 · The paper itself

Abstract

backgroundSubarachnoid hemorrhage (SAH) patients with cerebral autoregulation (CA) impairment at an early post-SAH period are at high risk of unfavorable outcomes due to delayed cerebral ischemia (DCI) or other complications. Limited evidence exists for an association between early-stage CA impairments and SAH patient outcomes. The objective of this prospective study was to explore associations between CA impairments detected in early post-SAH snapshot examinations and patient outcomes.

methodsThe pilot observational study included 29 SAH patients whose CA status was estimated 2-3 days after spontaneous aneurysm rupture and a control group of 15 healthy volunteers for comparison. Inflatable leg recovery boots (reboots.com, Germany) were used for the safe controlled generation of arterial blood pressure (ABP) changes necessary for reliable CA examination. At least 5 inflation‒deflation cycles of leg recovery boots with a 2-3 min period were used during examinations. CA status was assessed according to the delay time (∆T

resultsStatistically significant differences in ∆T

conclusionsA relatively small delay of ∆T

trial registrationClinicalTrials.gov Identifier: NCT06028906. Registered 31 August 2023 - Retrospectively registered, https://www. CLINICALTRIALS: gov/study/NCT06028906 .

Indexed as

BaroreflexCerebral blood flow autoregulationDelayed cerebral ischemiaSnapshot examinationSubarachnoid hemorrhageTranscranial Doppler

Identifiers

PMID38619783
PMCPMC11018731
OpenAlexW4394819896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.