Evidence map›Paper›PMID 38619745›Full record

ArticleMolecular neurobiology2024

Intrinsic ecto-5'-Nucleotidase/A

Andjela Stekic, Dejan Stevic, Tamara Dokmanovic, Marina Anastasov, Danica Popovic, Jelena Stanojevic, Milica Zeljkovic Jovanovic, Ivana Stevanovic, Nadezda Nedeljkovic, Milorad Dragic

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Protection From Demyelination by the Novel Adenosine Dual AJournal of cellular and molecular medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Andjela StekicLaboratory for Neurobiology, Faculty of Biology, University of Belgrade, Belgrade, Serbia.ORCID http://orcid.org/0000-0002-2353-2937
Dejan StevicLaboratory for Neurobiology, Faculty of Biology, University of Belgrade, Belgrade, Serbia.ORCID http://orcid.org/0009-0009-0837-1993
Tamara DokmanovicLaboratory for Neurobiology, Faculty of Biology, University of Belgrade, Belgrade, Serbia.
Marina AnastasovLaboratory for Neurobiology, Faculty of Biology, University of Belgrade, Belgrade, Serbia.
Danica PopovicLaboratory for Neurobiology, Faculty of Biology, University of Belgrade, Belgrade, Serbia.
Jelena StanojevicMedical Faculty of Military Medical Academy, University of Defense, 11 000, Belgrade, Serbia.ORCID http://orcid.org/0009-0000-7039-2212
Milica Zeljkovic JovanovicLaboratory for Neurobiology, Faculty of Biology, University of Belgrade, Belgrade, Serbia.ORCID http://orcid.org/0000-0002-5608-4384
Ivana StevanovicMedical Faculty of Military Medical Academy, University of Defense, 11 000, Belgrade, Serbia.
Nadezda NedeljkovicLaboratory for Neurobiology, Faculty of Biology, University of Belgrade, Belgrade, Serbia. nnedel@bio.bg.ac.rs.ORCID http://orcid.org/0000-0003-3046-0983
Milorad DragicLaboratory for Neurobiology, Faculty of Biology, University of Belgrade, Belgrade, Serbia. milorad.dragic@bio.bg.ac.rs.ORCID http://orcid.org/0000-0003-4855-6131
University of Belgrade · RSMilitary Medical Academy · RS

Funding

Ministry of Science, Technological Development and Innovation of Republic of Serbia 451-03-68/2023-14/200178University of Defence MFVMA/02/22-24
6 · The paper itself

Abstract

Experimental autoimmune encephalomyelitis (EAE) is widely used animal model of multiple sclerosis (MS). The disease is characterized by demyelination and neurodegeneration triggered by infiltrated autoimmune cells and their interaction with astrocytes and microglia. While neuroinflammation is most common in the spinal cord and brainstem, it is less prevalent in the cerebellum, where it predisposes to rapid disease progression. Because the induction and progression of EAE are tightly regulated by adenosinergic signaling, in the present study we compared the adenosine-producing and -degrading enzymes, ecto-5'-nucleotidase (eN/CD73) and adenosine deaminase (ADA), as well as the expression levels of adenosine receptors A

Indexed as

5'-NucleotidaseCerebellumEncephalomyelitis, Autoimmune, ExperimentalNeuroprotectionReceptor, Adenosine A1Adenosine DeaminaseAnimalsAstrocytesFemaleGliosisGPI-Linked ProteinsMiceMice, Inbred C57BLReceptor, Adenosine A2A5'-NucleotidaseAdenosine DeaminaseAdora1 protein, mouseGPI-Linked ProteinsNt5e protein, mouseReceptor, Adenosine A1Receptor, Adenosine A2AA1RA2ARAdenosineCerebellumEAEEcto-5`-nucleotidase/CD73

Identifiers

PMID38619745
OpenAlexW4394815132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.