ReviewMolecular neurobiology2024
Imaging Findings and Toxicological Mechanisms of Nervous System Injury Caused by Diquat.
Review in Molecular neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The trial behind it
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Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
- Charge reversible-natural light responsive nanoparticles enable targeted herbicide delivery and reduction of mammalian toxicity.Journal of advanced research · 2026Article
- Tea tree oil attenuates diquat-induced hepatotoxicity in chickens via suppression of the NF-κB-mediated inflammatory pathway.Veterinary research communications · 2026Article
- A retrospective analysis of paraquat and diquat poisoning: a single-center experience.Frontiers in medicine · 2026Article
- Diquat-induced organ toxicity: a focus on regulated cell death pathways and mitochondrial dysfunction.Frontiers in cell and developmental biology · 2026Review
- Molecular mechanisms in diquat-induced organs injury：insights into cell signaling and potential therapeutic agents.Cell biology and toxicology · 2025Review
- Impact of Diquat on the Intestinal Health and the Composition and Function of the Gut Microbiome.Antioxidants (Basel, Switzerland) · 2025Review
- Lung Transplant Success in Severe Diquat Poisoning: A Case Report.The American journal of case reports · 2025Article
- Diquat Induces Cell Death and dopamine Neuron Loss via Reactive Oxygen Species Generation inEnvironmental science & technology · 2025Article
- Case Report: A case of subarachnoid hemorrhage secondary to elbow intravenous injection of diquat poisoning in young male.Frontiers in public health · 2025Article
- Klotho mitigates diquat-induced myocardial injury in rats by activating Nrf2/ARE-mediated suppression of oxidative stress.American journal of translational research · 2025Article
- Diquat poisoning, maybe another cause of osmotic demyelination syndrome: case report and literature review.Frontiers in medicine · 2025Article
- Early Immune-Inflammatory Profiling and Prognostic Biomarkers in Patients with Acute Diquat Poisoning: A Multicenter Study with Exploratory Bioinformatics Analysis.Journal of inflammation research · 2025Article
- Effect of Diquat on gut health: molecular mechanisms, toxic effects, and protective strategies.Frontiers in pharmacology · 2025Review
- The Link Between Paraquat and Demyelination: A Review of Current Evidence.Antioxidants (Basel, Switzerland) · 2024Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Diquat (DQ) is a nonselective bipyridine herbicide with a structure resembling paraquat (PQ). In recent years, the utilization of DQ as a substitute for PQ has grown, leading to an increase in DQ poisoning cases. While the toxicity mechanism of DQ remains unclear, it is primarily attributed to the intracellular generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) through the process of reduction oxidation. This results in oxidative stress, leading to a cascade of clinical symptoms. Notably, recent reports on DQ poisoning have highlighted a concerning trend: an upsurge in cases involving neurological damage caused by DQ poisoning. These patients often present with severe illness and a high mortality rate, with no effective treatment available thus far. Imaging findings from these cases have shown that neurological damage tends to concentrate on the brainstem. However, the specific mechanisms behind this poisoning remain unclear, and no specific antidote exists. This review summarizes the research progress on DQ poisoning and explores potential mechanisms. By shedding light on the nerve damage associated with DQ poisoning, we hope to raise awareness, propose new avenues for investigating the mechanisms of DQ poisoning, and lay the groundwork for the development of treatment strategies for DQ poisoning. Trial registration number: 2024PS174K.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.