Evidence map›Paper›PMID 38619625›Full record

ArticleIntensive care medicine experimental2024

Hyperoxemia and hypoxemia impair cellular oxygenation: a study in healthy volunteers.

Bashar N Hilderink, Reinier F Crane, Bas van den Bogaard, Janesh Pillay, Nicole P Juffermans

Open access · goldAbstract read
In one paragraph

Article in Intensive care medicine experimental, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Bashar N HilderinkDepartment of Intensive Care, OLVG Hospital, Amsterdam, The Netherlands. b.n.hilderink@erasmusmc.nl.ORCID http://orcid.org/0000-0001-7684-6529
Reinier F CraneDepartment of Intensive Care, OLVG Hospital, Amsterdam, The Netherlands.
Bas van den BogaardDepartment of Intensive Care, OLVG Hospital, Amsterdam, The Netherlands.
Janesh PillayDepartment of Critical Care, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Nicole P JuffermansDepartment of Intensive Care, OLVG Hospital, Amsterdam, The Netherlands.
OLVG · NLErasmus MC · NLUniversity Medical Center Groningen · NL

Funding

European Society of Intensive Care Medicine NEXT grant
6 · The paper itself

Abstract

introductionAdministration of oxygen therapy is common, yet there is a lack of knowledge on its ability to prevent cellular hypoxia as well as on its potential toxicity. Consequently, the optimal oxygenation targets in clinical practice remain unresolved. The novel PpIX technique measures the mitochondrial oxygen tension in the skin (mitoPO

resultsDuring hypoxemia, SpO

conclusionsHypoxemia decreases mitoPO

Indexed as

Cellular oxygenationHyperoxemiaHyperoxiaHypoxemiaHypoxiaMitochondriaMitoPO2Oxygen therapy

Identifiers

PMID38619625
PMCPMC11018572
OpenAlexW4394813022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.