Evidence map›Paper›PMID 38619302›Full record

ArticleInfection and immunity2024

Flagellin-modulated inflammasome pathways characterize the human alveolar macrophage response to

Lara Lovelace-Macon, Sarah M Baker, Deirdre Ducken, Sudeshna Seal, Guilhem Rerolle, Diane Tomita, Kelly D Smith, Sandra Schwarz, T Eoin West

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Lara Lovelace-MaconDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA.
Sarah M BakerDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-0177-8135
Deirdre DuckenDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA.
Sudeshna SealDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA.
Guilhem RerolleDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA.
Diane TomitaDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA.
Kelly D SmithDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.
Sandra SchwarzInterfaculty Institute of Microbiology and Infection Medicine, University of Tuebingen, Tuebingen, Germany.
T Eoin WestDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-5503-7204
University of Washington · USUniversity of Tübingen · DE

Funding

HOST DEFENSE TRAINING IN ALLERGY AND INFECTIOUS DISEASEST32AI007044 · NIAID · UNIVERSITY OF WASHINGTON · PI DAVID Neal FREDRICKS · 1985 to 2026
$14.6M
Regulation of host inflammatory responses and outcome in melioidosis by TLR5R01HL113382 · NHLBI · UNIVERSITY OF WASHINGTON · PI WEST, TIMOTHY EOIN · 2012 to 2016
$2.6M
B. pseudomallei infection of the human lungR21AI130797 · NIAID · UNIVERSITY OF WASHINGTON · PI WEST, TIMOTHY EOIN · 2018 to 2019
$415k
NHLBI NIH HHS R01 HL113382NIAID NIH HHS R21 AI130797NIAID NIH HHS T32 AI007044
6 · The paper itself

Abstract

Melioidosis is an emerging tropical infection caused by inhalation, inoculation, or ingestion of the flagellated, facultatively intracellular pathogen

Indexed as

Burkholderia pseudomalleiFlagellinHost-Pathogen InteractionsInflammasomesMacrophages, AlveolarCells, CulturedHumansMelioidosisFlagellinInflammasomesalveolar macrophageBurkholderia pseudomalleiflagella

Identifiers

PMID38619302
PMCPMC11075458
OpenAlexW4394820202

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.