Evidence map›Paper›PMID 38619227›Full record

ArticleeLife2024

Guanidine production by plant homoarginine-6-hydroxylases.

Dietmar Funck, Malte Sinn, Giuseppe Forlani, Jörg S Hartig

Open access · goldAbstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Deciphering guanidine assimilation and riboswitch-based gene regulation in cyanobacteria for synthetic biology applications.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 3 countries.

Dietmar FunckDepartment of Chemistry, University of Konstanz, Konstanz, Germany.ORCID https://orcid.org/0000-0002-9855-0419
Malte SinnDepartment of Chemistry, University of Konstanz, Konstanz, Germany.ORCID https://orcid.org/0000-0002-3790-9686
Giuseppe ForlaniDepartment of Life Science and Biotechnology, University of Ferrara, Ferrara, Italy.ORCID https://orcid.org/0000-0003-2598-5718
Jörg S HartigDepartment of Chemistry, University of Konstanz, Konstanz, Germany.
University of Freiburg · DE

Funding

European Research Council 681777
6 · The paper itself

Abstract

Metabolism and biological functions of the nitrogen-rich compound guanidine have long been neglected. The discovery of four classes of guanidine-sensing riboswitches and two pathways for guanidine degradation in bacteria hint at widespread sources of unconjugated guanidine in nature. So far, only three enzymes from a narrow range of bacteria and fungi have been shown to produce guanidine, with the ethylene-forming enzyme (EFE) as the most prominent example. Here, we show that a related class of Fe

Indexed as

ArabidopsisMixed Function Oxygenases2-Aminoadipic AcidGuanidineGuanidinesHomoarginineProtein Isoforms2-Aminoadipic AcidallysineGuanidineGuanidinesHomoarginineMixed Function OxygenasesProtein Isoforms2-oxoglutarate-dependent dioxygenasealdehyde dehydrogenaseArabidopsis thalianaA. thalianabiochemistrychemical biologyE. coliFe2+guanidinehomoarginineplant biology

Identifiers

PMID38619227
PMCPMC11018352
OpenAlexW4387541026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.