Evidence map›Paper›PMID 38618679›Full record

ArticleHaematologica2024

Molecular responses in decitabine- and decitabine/ venetoclax-treated patients with acute myeloid leukemia and myelodysplastic syndromes.

Agata Gruszczynska, Abhishek Maiti, Christopher A Miller, Sai Mukund Ramakrishnan, Daniel C Link, Geoffrey L Uy, Allegra A Petti, Kala Hayes, Courtney D DiNardo, Farhad Ravandi and 5 more

Abstract readLetter
In one paragraph

Article in Haematologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Agata GruszczynskaDepartment of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri 63110.
Abhishek MaitiDepartment of Leukemia, MD Anderson Cancer Center, Houston, Texas 77030.
Christopher A MillerDepartment of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri 63110.
Sai Mukund RamakrishnanDepartment of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri 63110.
Daniel C LinkDepartment of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri 63110.
Geoffrey L UyDepartment of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri 63110.
Allegra A PettiDepartment of Neurosurgery, Washington University School of Medicine, St. Louis, Missouri 63110.
Kala HayesDepartment of Leukemia, MD Anderson Cancer Center, Houston, Texas 77030.
Courtney D DiNardoDepartment of Leukemia, MD Anderson Cancer Center, Houston, Texas 77030.
Farhad RavandiDepartment of Leukemia, MD Anderson Cancer Center, Houston, Texas 77030.
Timothy J LeyDepartment of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri 63110.
David H SpencerDepartment of Pathology, Washington University School of Medicine, St. Louis, Missouri 63110.
Feng GaoDepartment of Surgery, Division of Public Health Sciences, Washington University School of Medicine, St. Louis, Missouri 63110.
Marina Y KonoplevaAlbert Einstein College of Medicine, Bronx, New York 10461.
John S WelchDepartment of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri 63110; A2 Biotherapeutics, Agoura Hills, California 91301 (work completed while at Washington University). jwelch@a2biotherapeutics.com.

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
Specimen Acquistition and Expression ProfilingP01CA101937 · NCI · WASHINGTON UNIVERSITY · PI PAYTON, JACQUELINE E. · 2003 to 2023
$58.8M
Targeting the Bone Marrow Microenvironment In Acute Lymphocytic LeukemiaP50CA171963 · NCI · WASHINGTON UNIVERSITY · PI Daniel C Link · 2013 to 2026
$31.6M
Molecular Pathogenesis of Acute Myeloid LeukemiaR35CA197561 · NCI · WASHINGTON UNIVERSITY · PI Timothy J. Ley · 2015 to 2026
$11.0M
Targeting apoptosis in high-risk AML and MDS with BCL-2 inhibitor Venetoclax and optimized 10-day Decitabine regimenR01CA235622 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KONOPLEVA, MARINA Y, SPENCER, DAVID H · 2019 to 2024
$1.8M
Dysregulated genome architecture in acute myeloid leukemiaR37CA259359 · NCI · WASHINGTON UNIVERSITY · PI David H Spencer · 2022 to 2026
$1.8M
COMPREHENSIVE INFORMATIC ANALYSES OF AML GENOMES AND EPIGENOMESR50CA211782 · NCI · WASHINGTON UNIVERSITY · PI Christopher A Miller · 2017 to 2026
$1.5M
NCI NIH HHS P01 CA101937NCI NIH HHS P30 CA091842NCI NIH HHS P50 CA171963NCI NIH HHS R01 CA235622NCI NIH HHS R35 CA197561NCI NIH HHS R37 CA259359NCI NIH HHS R50 CA211782
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsBridged Bicyclo Compounds, HeterocyclicDecitabineLeukemia, Myeloid, AcuteMyelodysplastic SyndromesSulfonamidesAdultAgedFemaleHumansMaleMiddle AgedTreatment OutcomeBridged Bicyclo Compounds, HeterocyclicDecitabineSulfonamidesvenetoclax

Identifiers

PMID38618679
PMCPMC11290502

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.