Evidence map›Paper›PMID 38618568›Full record

ArticlePeerJ2024

Xi Zou, Jun Zhang, Yong Wang, Dong Zhou, Guohua Deng, Zhinan Liu

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Xi ZouChangzhou Medical Center, Changzhou, China.
Jun ZhangThe Third People's Hospital of Changzhou, Changzhou, China.
Yong WangNantong First People's Hospital, Nantong, China.
Dong ZhouThe Third People's Hospital of Changzhou, Changzhou, China.
Guohua DengThe Third People's Hospital of Changzhou, Changzhou, China.
Zhinan LiuThe Third People's Hospital of Changzhou, Changzhou, China.
Changzhou Third People's Hospital · CNChangzhou No.2 People's Hospital · CNNantong University · CN

Funding

Changzhou Medical Center of Nanjing Medical UniversityJiangsu Province Traditional Chinese Medicine Technology Development ProjectProject of Changzhou Health CommissionScience and Technology Project of ChangzhouYoung Talent Development Plan of Changzhou Health Commission
6 · The paper itself

Abstract

Background: Single nucleotide polymorphisms (SNPs), as the most abundant form of DNA variation in the human genome, contribute to age-related cataracts (ARC) development. Apoptosis of lens epithelial cells (LECs) is closely related to ARC formation. Insulin-like growth factor 1 (IGF1) contributes to cell apoptosis regulation. Moreover, IGF1 was indicated to exhibit a close association with cataract formation. Afterward, an investigation was conducted to examine the correlation between polymorphisms in Methods: The present investigation was a case-control study. Venous blood draws were collected from the participants for DNA genotyping. Lens capsule samples were collected to detect mRNA and apoptosis. TaqMan RT-PCR was used to detect Results: We found that the G allele frequency in the Conclusion: The susceptibility to ARC was related to

Indexed as

CataractInsulin-Like Growth Factor ICase-Control StudiesDNAHumansPolymorphism, Single NucleotideRNA, MessengerDNAInsulin-Like Growth Factor IRNA, MessengerAge-related cataract (ARC)ApoptosisInsulin-like growth factor 1(IGF1)Lens epithelial cells (LECs)Single nucleotide polymorphisms (SNPs)

Identifiers

PMID38618568
PMCPMC11011587
OpenAlexW4394611907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.