ReviewInternational journal of physiology, pathophysiology and pharmacology2024
Extracellular vesicles and their therapeutic applications: a review article (part1).
Review in International journal of physiology, pathophysiology and pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 30 citations in OpenAlex.
- Quality Evaluation Considerations for Stem Cell-Derived Extracellular Vesicles-Based Therapeutic Products in China.Journal of extracellular vesicles · 2026Review
- [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026Article
- Using artificial intelligence for distinguishing benign and malignant vertebral compression fractures by computed tomography: a scoping review.International journal of burns and trauma · 2026Review
- Recent Evidence for Orthobiologics Combined with Hydrogels for Joint Tissue Regeneration: Focus on Osteoarthritis.Gels (Basel, Switzerland) · 2025Review
- Bioengineered Tumor-Derived Extracellular Vehicles Suppressed Colorectal Cancer Liver Metastasis and Bevacizumab Resistance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Adaptations of Bacterial Extracellular Vesicles in Response to Antibiotic Pressure.International journal of molecular sciences · 2025Review
- Artificial intelligence in automated detection of lung nodules: a narrative review.International journal of physiology, pathophysiology and pharmacology · 2025Review
- The role of nuclear medicine in neurodegenerative diseases: a narrative review.American journal of neurodegenerative disease · 2025Review
- A review of the use of oral anticoagulants in individuals with atrial fibrillation who had experienced intracranial hemorrhage in the past.International journal of physiology, pathophysiology and pharmacology · 2025Review
- Advances in nanotechnology for targeted drug delivery in neurodegenerative diseases.American journal of neurodegenerative disease · 2025Review
- Cardiac magnetic resonance imaging in myocardial infarction with non-obstructed coronary arteries: diagnostic and prognostic value.American journal of cardiovascular disease · 2025Review
- Evaluation of the success rate of the semi-sitting position compared with the supine position in the emergency intubation of traumatic patients.International journal of burns and trauma · 2025Article
- Using ultrasonographic features in pediatric Crohn's disease activity index severity.International journal of physiology, pathophysiology and pharmacology · 2025Article
- Early fetal sex determination: the predictive value of anogenital distance and fetal heart rate in first-trimester ultrasound.American journal of neurodegenerative disease · 2025Article
- The use of radiopharmaceuticals in targeted cancer therapy: a narrative review.International journal of physiology, pathophysiology and pharmacology · 2025Review
- Detection and Characterization of Extracellular Vesicles in Sputum Samples of COPD Patients.Journal of personalized medicine · 2024Article
- Safety and effectiveness of micropigmentation skin grafting using the Meek method.International journal of burns and trauma · 2024Review
- Investigating the effect of cancer medication in the development of Takotsubo cardiomyopathy.American journal of cardiovascular disease · 2024Review
- Comparison of PET/CT and PET/MRI in central nervous system tumors, a narrative review.International journal of physiology, pathophysiology and pharmacology · 2024Review
- Evaluating antiarrhythmic drugs for managing infants with supraventricular tachycardia; a review.American journal of cardiovascular disease · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extracellular vesicles (EVs) have emerged as a captivating field of study in molecular biology with diverse applications in therapeutics. These small membrane-bound structures, released by cells into the extracellular space, play a vital role in intercellular communication and hold immense potential for advancing medical treatments. EVs, including exosomes, microvesicles, and apoptotic bodies, are classified based on size and biogenesis pathways, with exosomes being the most extensively studied. The aim of this study was to examine the molecular secretory pathway of exosomes and to discuss the medical applications of exosomes and the methods for employing them in laboratory models. The therapeutic potential of EVs has garnered significant attention. Their unique properties, such as stability, biocompatibility, and capacity to traverse biological barriers, make them promising vehicles for targeted drug delivery. By engineering EVs to carry specific cargo molecules, such as therapeutic proteins, small interfering Ribonucleic Acid (RNAs) (siRNAs), or anti-cancer drugs, researchers can enhance drug stability and improve their targeted delivery to specific cells or tissues. This approach has the potential to minimize off-target effects and increase therapeutic efficacy, offering a more precise and effective treatment strategy. EVs represent a captivating and rapidly evolving field with significant therapeutic implications. Their role in intercellular communication, targeted drug delivery, and regenerative medicine makes them valuable tools for advancing medical treatments. As our understanding of EV biology and their therapeutic applications continues to expand, we can expect remarkable advancements that will revolutionize the field of medicine and lead to more personalized and effective therapies.
Indexed as
Identifiers
38618492PMC11007590W4394820099What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.